PMID: 8588063Jul 1, 1995Paper

Serum sodium stabilizing effect of enalapril after standard water load in a patient with a history of self-induced water intoxication

Progress in Neuro-psychopharmacology & Biological Psychiatry
C S SebastianN K Gulati

Abstract

1. A 21 day prospective placebo controlled double blind cross over trial of enalapril was studied in a normonatremic patient with a known history of SIWI. 2. At the end of each prophylactic treatment, the patient was challenged with a water load of 20 ml/kg. 3. The mean serum sodium of 140.111 mmol/L on prophylactic enalapril was significantly higher than the 137.6 mmol/L on placebo (p = 0.0015). 4. After a water load, the mean serum sodium on enalapril was 137.6 mmol/L, compared to 133.833 mmol/L (p = 0.0015) on placebo.

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Jan 1, 1987·Journal of Cardiovascular Pharmacology·D J Campbell
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Apr 1, 1993·The American Journal of Psychiatry·M S Shutty, R A Leadbetter

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Citations

Jan 31, 2002·Progress in Neuro-psychopharmacology & Biological Psychiatry·Nicholas J DelvaJames A Owen
Dec 9, 1995·Journal of Management in Medicine·K Hurst
Apr 23, 2003·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Takahiro ShinkaiJun Nakamura

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