Serum testosterone levels and reference ranges in reproductive-age women.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
C AyalaS M Petak

Abstract

To determine the levels of serum testosterone and dehydroepiandrosterone sulfate (DHEAS) in women with no clinical signs of hyperandrogenism and no history of glucocorticoid or oral contraceptive use and to compare these levels with the reference ranges provided by commercial laboratories. We undertook a cross-sectional retrospective study of 271 reproductive-age women encountered at an endocrinology clinic for complaints of potential thyroid problems. Serum testosterone and DHEAS levels were determined, and statistical analyses were performed. The serum testosterone level in women with no acne, hirsutism, or menstrual dysfunction was 14.1 +/- 0.9 ng/dL (mean +/- standard error of the mean) (95% confidence interval [CI] = 12.4 to 15.8). This group was considered our study reference population. In women with menstrual dysfunction but no acne or hirsutism, the mean testosterone level was significantly higher (17.9 +/- 1.1 ng/dL; 95% CI = 15.7 to 20.0; P<0.002); with mild hirsutism, it further increased (38.4 +/- 5.1 ng/dL; 95% CI = 27.4 to 49.4; P<0.005); and with moderate to severe hirsutism, it was still higher (49.0 +/- 2.3 ng/dL; 95% CI = 44.4 to 53.6; P<0.003). Serum DHEAS levels showed similar patterns. The upper limit (mea...Continue Reading

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Citations

Aug 28, 2007·Lancet·Robert J NormanTheresa E Hickey
Mar 22, 2005·Journal of Cutaneous Medicine and Surgery·Maha Haroun
Oct 14, 2006·American Journal of Human Biology : the Official Journal of the Human Biology Council·Sari M Van Anders, Neil V Watson
Dec 18, 2009·The Journal of Clinical Endocrinology and Metabolism·Elisabet Stener-VictorinClaes Ohlsson
May 26, 2005·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·UNKNOWN American Association of Clinical Endocrinologists Polycystic Ovary Syndrome Writing Committee
Aug 28, 2003·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·N F GoodmanUNKNOWN American Association of Clinical Endocrinologists Hyperandrogenic Disorders Task Force
Mar 16, 2001·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·L J Rodriguez-Rigau

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