Serum thyrotrophin concentration: an unreliable test for detection of early hypothyroidism after thyroidectomy.

British Medical Journal
G HennemannT J Visser

Abstract

Three groups of patients who had undergone subtotal thyroidectomy for Graves's disease, toxic multinodular goitre, or euthyroid multinodular goitre 12 to 15 years before and in whom a normal serum thyroxine (T-4) level was found were each divided into two subgroups on the basis of a normal or a raised serum thyrotrophin concentration. There was no difference in mean serum T-4 concentration between patients with normal and those with raised serum thyrotrophin concentrations, and the values were similar to the mean T-4 values of the normal population. The mean serum triiodothyronine values of all groups were higher than normal, but the mean values of the groups with a normal and a raised serum thyrotrophin were similar. After thyroidectomy a mildly raised serum thyrotrophin does not in itself indicate the presence of hypothyroidism.

References

Jan 4, 1975·British Medical Journal·D EveredP H Dickinson

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Citations

Apr 16, 1977·British Medical Journal·T J WilkinJ S Beck
May 1, 1978·World Journal of Surgery·W MichieJ E Pollet
Feb 1, 1981·The British Journal of Surgery·S NoguchiA Noguchi
Nov 1, 1982·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J A Van Best
Jan 1, 1979·Acta Medica Scandinavica·M Blichert-ToftC K Axelsson

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