PMID: 8599325Apr 1, 1996Paper

Serum transferrin receptor concentrations in women with mild malnutrition

The American Journal of Clinical Nutrition
S KuvibidilaL Yu

Abstract

We determined the influence of undernutrition on blood soluble transferrin receptor (sTfR) concentrations, an indicator of iron deficiency, in 99 Zairean women (aged 16-45 y) without inflammation. They were recruited during a survey on iron deficiency in rural Bas-Zaire. sTfR was measured by enzyme immunoassay, and indicators of nutritional status [albumin, transthyretin (or prealbumin), and retinol binding protein] were measured by radial immunodiffusion. Undernutrition was diagnosed if the concentration of any one of the indicators was below normal: albumin < 35 g/L, transthyretin < 160 mg/L, and retinol binding protein < 30 mg/L. The sTfR concentration ranged from 1.89 to 19.1 mg/L (mean: 8.7 mg/L). Mean values for indicators of nutritional status, serum ferritin, and transferrin saturation were within the normal range for health subjects. Regardless of the iron status (iron sufficiency, anemia, or iron deficiency with or without anemia) and whether women were pregnant or nonpregnant, undernutrition did not significantly reduce sTfR concentrations. A higher percentage (80%) of iron-deficient women with two or three protein values below normal had sTfR concentrations > 8 mg/L (which are suggestive of iron-deficiency erythropo...Continue Reading

Citations

Sep 7, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·R BeesleyS Parton
Jul 30, 2003·The American Journal of Clinical Nutrition·Olga P GarciaLindsay H Allen
Feb 8, 2002·Clinical Chemistry and Laboratory Medicine : CCLM·G RayaG Siest
Oct 11, 2017·The American Journal of Tropical Medicine and Hygiene·Esto BahizirePhilippe Donnen
Jan 20, 2004·Tropical Medicine & International Health : TM & IH·B RitchieD R Brewster

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