Serum triglyceride level is an important predictor of early prognosis in patients with acute ischemic stroke

Journal of the Neurological Sciences
Kang-Ho ChoiKi-Hyun Cho

Abstract

Some recent studies have shown that poor outcomes after acute ischemic stroke (AIS) were closely related to lower serum triglyceride (TG) levels, not hypertriglyceridemia. However, hypertriglyceridemia has been shown to be an independent predictor for poor outcome in patients with coronary artery disease. This study attempted to evaluate the association between serum TG levels and early prognosis of AIS. We enrolled 736 consecutive patients with AIS. Based on the TG level, patients were divided into 5 groups based on the guidelines of the National Cholesterol Education Program (NCEP). We defined early neurological deterioration (END) as a 4-point or greater deterioration of the NIH stroke scale (NIHSS) score and early clinical improvement (ECI) as a 4-point reduction of NIHSS within a week after symptom onset. We compared patients with END, ECI, and neither END nor ECI. The risk of END was significantly higher in the hyperTG and hypoTG groups compared with the normal group. The percentages of ECI were significantly lower in the hypoTG, borderline, and hyperTG groups compared with the normal group. For END, the multivariable adjusted odds ratios were significantly higher in the hypoTG, borderline, and hyperTG groups compared wit...Continue Reading

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Citations

Apr 29, 2014·The American Journal of Emergency Medicine·Leng-Chieh LinJen-Tsung Yang
Sep 10, 2015·BioMed Research International·Sang Hoon LeeKyung Soo Chung
Jul 3, 2013·Journal of the Neurological Sciences·Ryota TanakaTakao Urabe
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Jan 1, 2013·Neuroscience Journal·Minal JainLatha Ganti Stead
Nov 20, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Q-W DengF-L Yan

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