Serum uric acid and related factors in 500 hospitalized subjects

Metabolism: Clinical and Experimental
F SaggianiE Bonora

Abstract

The study purpose was to determine the following in a large sample of hospitalized patients: (1) the prevalence of hyperuricemia, (2) the association of hyperuricemia with other metabolic disorders, and (3) the factors independently predicting hyperuricemia. Five hundred adult patients (250 men and 250 women) were randomly selected from those admitted as inpatients over a period of 5 months. In all patients, body mass index (BMI), blood pressure, and serum glucose, lipid, creatinine, urea nitrogen, and urate concentrations were measured. The presence of diseases or use of medications known to affect serum urate levels were recorded. The mean level of serum urate was 5.6 mg/dL in the whole sample, 6.0 mg/dL in men and 5.3 mg/dL in women (P = .003, men v women). The prevalence of hyperuricemia was 27.6% (28.8% and 26.4% in men v women, P = nonsignificant). A definite or probable secondary hyperuricemia was found in 87.7% of the subjects. Hyperuricemia was rarely isolated (21%), whereas it was frequently associated with hypertension (60.1%), hyperlipidemia (31.2%), diabetes (28.3%), and obesity (21.7%). In 26.8% of the subjects, hyperuricemia was associated with two metabolic disorders, in 13.8% with three, and in 2.9% with four. ...Continue Reading

References

May 1, 1979·Circulation·V W PerskyH A Lindberg
Apr 1, 1976·Journal of the American Geriatrics Society·R B GreenblattC S Bohler
Sep 1, 1987·Diabetologia·M ModanA Lusky
Jan 1, 1985·American Journal of Epidemiology·F N BrandW P Castelli
May 1, 1972·Journal of Chronic Diseases·J ZalokarD Kuntz
Feb 24, 1973·British Medical Journal·A NichollsJ T Scott
Feb 1, 1974·Journal of Chronic Diseases·J ZalokarD Kuntz
Feb 1, 1971·Clinica Chimica Acta; International Journal of Clinical Chemistry·N Kageyama
Jul 31, 1982·Lancet·J B Herman, U Goldbourt
Dec 1, 1980·Annals of Internal Medicine·F H MesserliG G Aristimuno
Jul 1, 1993·Journal of Internal Medicine·I ZavaroniG M Reaven

❮ Previous
Next ❯

Citations

Feb 8, 2002·International Journal of Nursing Practice·Shih-Wei LaiKim-Choy Ng
Jun 1, 2005·European Journal of Heart Failure·Marcelo E OchiaiJosé A F Ramires
Sep 15, 2005·Internal Medicine·Ryuichi KawamotoAtsushi Kamitani
Dec 6, 2005·Irish Journal of Medical Science·S W Lai, K C Ng
May 9, 2008·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Pantea EbrahimpourBagher Larijani
Jan 20, 2009·Endocrine Reviews·Richard J JohnsonTakahiko Nakagawa
Apr 29, 2010·Current Rheumatology Reports·Marilda MazzaliRichard J Johnson
May 20, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·S W LaiK C Ng
Apr 6, 2016·Endocrine Research·Luis E Simental-MendíaFernando Guerrero-Romero
Mar 8, 2002·Nursing & Health Sciences·S W LaiK C Ng
Dec 29, 2000·Scandinavian Journal of Rheumatology·Y SunT Stürmer
Jul 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Tae Woo YooDong Geuk Keum
Jun 3, 2009·Southern Medical Journal·Shih-Wei LaiKuan-Fu Liao
May 5, 2006·Current Hypertension Reports·Xiaoyan ZhouEdward D Frohlich
Jul 17, 2004·Southern Medical Journal·Shih-Wei Lai, Kim-Choy Ng
Jan 13, 2004·Journal of Pediatric Endocrinology & Metabolism : JPEM·Christian DenzerMartin Wabitsch
Feb 2, 2006·Annals of Medicine·Enzo Bonora
Feb 19, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R J JohnsonA B Fogo
Mar 20, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Giuseppe LippiGiovanni Targher
Apr 30, 2008·Metabolism: Clinical and Experimental·Michiaki FukuiNaoto Nakamura

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.