Serum uric acid level is not associated with osteoarthritis in Korean population: data from the Seventh Korea National Health and Nutrition Examination Survey 2016

Rheumatology International
Seong-Kyu KimJung-Yoon Choe

Abstract

There is an ongoing debate regarding the relationship between uric acid and osteoarthritis (OA). Therefore, we sought to clarify this association using data from the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-1) 2016 in the Korean population. A total of 5842 subjects over 19 years old were analyzed from the KNHANES VII-1 2016 data, which was conducted by the Korean Centers for Disease Control and Prevention. All of the statistical analyses were performed on the basis of a sampling weight that represents the entire Korean population. The data were described as case numbers with weighted percentages (%), and means with standard errors (SE). The association between OA and the serum uric acid level was statistically analyzed using univariate and multivariate logistic regression methods. A total of 669 subjects (8.6%) had OA, of which 557 were female (14.0%), and 112 male (3.0%). OA was more frequent in female than male subjects (n = 557, 82.6% in women) (p < 0.001). The serum uric acid level was significantly higher in subjects without OA than those with OA (p < 0.001). Subgroup analysis in female subjects demonstrated that the serum uric acid level in OA was much higher than those without OA [4.48 ...Continue Reading

References

Jul 1, 1988·Annals of Internal Medicine·D T FelsonR F Meenan
Jan 1, 1983·Arthritis and Rheumatism·P A SimkinE B Larson
Dec 29, 2000·Scandinavian Journal of Rheumatology·Y SunT Stürmer
Mar 23, 2005·Osteoarthritis and Cartilage·R C KinneyB D Boyan
Jun 28, 2005·Osteoarthritis and Cartilage·Velandai K SrikanthGraeme Jones
Oct 6, 2005·Annals of Internal Medicine·Hyon K ChoiUNKNOWN American Physiological Society
Jan 13, 2006·Nature·Fabio MartinonJürg Tschopp
Oct 10, 2006·Vitamins and Hormones·Claire JacquesCem Gabay
Mar 24, 2009·Annual Review of Immunology·Fabio MartinonJürg Tschopp
Jan 20, 2011·Proceedings of the National Academy of Sciences of the United States of America·Anna E DenobleVirginia B Kraus
Aug 8, 2012·Joint, Bone, Spine : Revue Du Rhumatisme·Edward Roddy, Michael Doherty
Dec 25, 2012·Biology of Sex Differences·Daniel P NicolellaWendy M Kohrt
Nov 16, 2014·Annals of the Rheumatic Diseases·Chang-Fu KuoMichael Doherty
Dec 17, 2015·International Journal of Molecular Sciences·Hyun Sook HwangHyun Ah Kim
Jan 9, 2016·Rheumatology International·Xiang DingGuang-Hua Lei
May 20, 2016·Nature Reviews. Rheumatology·Richard F LoeserBrian O Diekman
Feb 22, 2017·Arthritis & Rheumatology·Svetlana KrasnokutskyMichael H Pillinger

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