PMID: 5919366Sep 1, 1966

Serum uric acid levels in normal pregnancy with observations on the renal excretion of urate in pregnancy

Journal of Clinical Pathology
J A BoyleW W Buchanan

Abstract

Serum uric acid estimations were performed in 106 healthy pregnant women during early, middle, and late pregnancy, using an automated colorimetric method. The mean serum uric acid level was significantly lower during early and middle pregnancy than that of 64 age-matched female controls. The serum uric acid level was not significantly different in late pregnancy from the control group. Studies of the daily urinary urate excretion in 31 pregnant women showed normal urinary urate excretion in early pregnancy and enhanced renal loss of urate in middle and late pregnancy. It appears that the renal clearance of urate in pregnancy is high, especially in the middle period when the serum level is low in spite of the increased production of uric acid by the foetus.

References

Feb 1, 1953·Radiology·I J GREENHUTJ A CAMPBELL
May 1, 1965·Annals of the Rheumatic Diseases·M J BUCHANANB S ROSE
Apr 1, 1962·The Journal of Obstetrics and Gynaecology of the British Empire·F I LEE, F E LOEFFLER
Dec 1, 1932·Archives of Disease in Childhood·D Nabarro, A G Signy

Citations

May 25, 2013·International Journal of Obstetric Anesthesia·V P KovachevaL C Tsen
Jul 10, 2003·Clinics in Laboratory Medicine·Deirdre J LyellLinda C Giudice
Nov 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·B N AmesP Hochstein
Mar 25, 1978·British Medical Journal·W Dunlop, J M Davison
Oct 15, 1975·Experientia·Y NishidaT Nishizawa
Jan 1, 1977·British Journal of Obstetrics and Gynaecology·W Dunlop, J M Davison
Sep 1, 1972·Kidney International·E W HolmesJ B Wyngaarden
Aug 1, 1980·Kidney International·J M Davison, W Dunlop
May 23, 2015·Journal of Human Hypertension·Q ChenM Zhao
Jun 23, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Corine M KoopmansBen W J Mol
Feb 16, 2008·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Jane WoolcockRobert Ogle
Aug 1, 1994·Urology·K R Loughlin
Oct 1, 1968·The American Journal of Medicine·A R MyersW M Mikkelsen
Sep 1, 1972·The American Journal of Medicine·M L GreeneJ E Seegmiller
Oct 1, 1982·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T R Varma
Nov 1, 1982·The Australian & New Zealand Journal of Obstetrics & Gynaecology·P E HickmanJ M Potter
Sep 9, 2010·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Talya WolakEyal Sheiner
Jun 3, 1998·American Journal of Obstetrics and Gynecology·K H LimS J Kilpatrick
Jan 1, 1996·American Journal of Obstetrics and Gynecology·A ManyJ M Roberts
Feb 4, 2012·Gynecologic and Obstetric Investigation·Yoichiro AkahoriYuji Hiramatsu
Oct 27, 2017·Scandinavian Journal of Clinical and Laboratory Investigation·Martin RischLorenz Risch
Aug 1, 1989·The Australian & New Zealand Journal of Obstetrics & Gynaecology·J Carter, A Child
Jan 1, 1976·Journal of Clinical Pathology. Supplement (Royal College of Pathologists)·C W RedmanJ Bonnar
Feb 1, 1984·British Journal of Obstetrics and Gynaecology·T LindP R Philips
Jan 1, 1988·Cardiovascular Drugs and Therapy·J N Lessem
Aug 11, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Ayodele Odutayo, Michelle Hladunewich
Jan 1, 1971·Acta Medica Scandinavica·E J Dorhout MeesM G Nieuwenhuis
Sep 1, 1992·The Journal of Urology·J D Denstedt, H Razvi
May 23, 2014·Physiological Reports·Ichiro UeharaHiroyuki Sakurai
Aug 17, 2012·Expert Review of Cardiovascular Therapy·Gianni Bellomo

Related Concepts

Colorimetry
Kidney
Urate

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Related Papers

Biulleten' eksperimental'noĭ biologii i meditsiny
N S SapronovA B Siniukhin
Baillière's Clinical Obstetrics and Gynaecology
J C Atherton, R Green
British Journal of Obstetrics and Gynaecology
W Dunlop, J M Davison
Diabetic Medicine : a Journal of the British Diabetic Association
S M MacRuryA C MacCuish
© 2021 Meta ULC. All rights reserved