Serum zinc concentration in patients with acute myocardial infarction in percutaneous coronary intervention era

PloS One
Toshitaka OkabeMasahiko Ochiai

Abstract

There were few studies that investigated the association between serum zinc concentration and acute myocardial infarction (AMI) in percutaneous coronary intervention era. We assessed the relationships between serum zinc concentration, complications, and prognosis in AMI patients after primary percutaneous coronary intervention. We conducted a single-center, prospective, observational study including 50 patients with AMI. We divided patients into two groups (High-zinc group and Low-zinc group) by median serum zinc concentration and compared two groups about clinical outcomes up to 1 year follow up. The mean age of patients was 66.2 ± 11.8 years old. Patients in the Low-zinc group had ST-segment elevation more frequently than those in the High-zinc group (96.0% vs. 72.0%, P = 0.02). All-cause mortality at 1 year was similar in both groups (P (log-rank) = 0.33). However, the lengths of hospital stay and in coronary care unit were longer in patients in the Low-zinc group than in those in the High-zinc group (15.6 ± 9.2 days vs. 11.9 ± 2.9 days, P = 0.06; 3.9 ± 2.8 days vs. 2.3 ± 0.8 days, P = 0.01). Multivariate regression analysis showed that low serum zinc concentration was associated with the use of cardiac or respiratory assist...Continue Reading

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Jan 1, 2017·International Journal of Cardiology·Toshitaka OkabeMasahiko Ochiai

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Citations

Jan 21, 2021·Biological Trace Element Research·Stefan RodicCarl van Walraven
Feb 5, 2022·Cardiology in Review·Farhana BegumMarta Christov

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