Severe acute respiratory failure secondary to acute fibrinous and organizing pneumonia requiring mechanical ventilation: a case report and literature review

Respiratory Care
Sonia López-CuencaAndrés Esteban

Abstract

A 27-year-old woman was admitted to our ICU with acute hypoxemic respiratory failure and criteria for ARDS. Despite an F(IO(2)) of 1.0 and a lung protective strategy, the patient died on day 15 without any improvement. The relatives gave consent for post-mortem analysis. The histopathologic study of the lung showed findings typical of an acute fibrinous and organizing pneumonia. Apropos of this case we performed a PubMed search. We found 13 articles, including a total of 29 patients. Acute fibrinous and organizing pneumonia is an unusual cause of acute lung injury. The diagnostic criterion is histopathologic. There is little information regarding the pathophysiology of this illness. Important questions remain regarding this disease, including predisposing factors and management. Patients who require mechanical ventilation have poor outcomes.

Citations

Apr 26, 2013·American Journal of Respiratory and Critical Care Medicine·Miranda ParaskevaGlen P Westall
Sep 16, 2014·American Journal of Respiratory and Critical Care Medicine·Filippo LococoMassimiliano Paci
Dec 3, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Maria A KokosiAthol U Wells
Nov 12, 2016·Revue de pneumologie clinique·G RivalG Capellier
Dec 6, 2019·Medicine·Kaige WangDeyun Cheng
Apr 25, 2020·Intensive Care Medicine·Marie-Christine CopinUNKNOWN Lille COVID-19 ICU and Anatomopathology Group
Dec 21, 2018·World Journal of Clinical Cases·Ya-Jing NingRong-Yu Liu
Mar 27, 2021·Medicina intensiva·H MerdjiUNKNOWN CRICS TRIGGERSEP Group (Clinical Research in Intensive Care, Sepsis Trial Group for Global Evaluation, Research in Sepsis)
Jun 2, 2021·Medicina Intensiva·H MerdjiUNKNOWN CRICS TRIGGERSEP Group (Clinical Research in Intensive Care, Sepsis Trial Group for Global Evaluation, Research in Sepsis)
Jun 1, 2021·Medicina intensiva·H MerdjiUNKNOWN CRICS TRIGGERSEP Group (Clinical Research in Intensive Care, Sepsis Trial Group for Global Evaluation, Research in Sepsis)

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