Severe alcohol-induced liver disease and the alcohol dependence syndrome

Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism
Stewart SmithNick Sheron

Abstract

To examine the hypothesis that patients who present in the UK to detoxification services differ from patients who present with severe alcohol-induced liver disease (ALD) with respect to severity of dependence on alcohol and other features of their drinking history. Levels of alcohol dependence were assessed in 34 patients with severe ALD, all of whom were cirrhotic, and 34 subjects from a residential alcohol detox centre in Southampton using the Severity of Alcohol Dependence Questionnaire (SADQ). During interview, various aspects of participants' alcohol consumption were recorded, including total monthly consumption, whom they usually drank with and where, and, if applicable, what caused them to start drinking heavily. Social circumstances were also noted, including participants' employment and marital status. Among ALD patients, 58% scored none/mild on the SADQ, 32% moderate and 9% severe. In contrast, 76% of the detox group were graded severe and 34% moderate (P < 0.001). ALD patients were also significantly older, had lower scores on the Alcohol Use Disorders Identification Test, tended to drink less alcohol, were more likely to be in a stable relationship, were less likely to be unemployed and gave different reasons for st...Continue Reading

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Citations

Apr 4, 2008·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Sam J ThomsonJin-Yong Kang
Mar 17, 2009·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Dermot GleesonRobert J Peck
Apr 7, 2007·Current Opinion in Gastroenterology·Adrian Reuben
Dec 2, 2010·Clinical Medicine : Journal of the Royal College of Physicians of London·S D RyderN R Wright
Sep 22, 2010·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Benjamin VyssokiOtto M Lesch
Apr 25, 2009·Alcoholism, Clinical and Experimental Research·Giovanni AddoloratoLorenzo Leggio
May 28, 2011·International Journal of Geriatric Psychiatry·Barbara Jean KilbourneRobert Levine
Mar 10, 2017·Scandinavian Journal of Gastroenterology·Jon Kristinn NielsenEinar S Björnsson
Sep 20, 2011·Journal of Psychopharmacology·Ruth Weissenborn, David J Nutt
Jan 24, 2018·World Journal of Hepatology·Gro AskgaardJanne S Tolstrup
May 10, 2017·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Kerry J FoxDonna C Jessop
Oct 8, 2016·The American Journal of Drug and Alcohol Abuse·Annie Roy-CharlandSherry H Stewart

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