Severe anemia from heavy menstrual bleeding requires heightened attention

American Journal of Obstetrics and Gynecology
Anita L Nelson, Julia J Ritchie

Abstract

The objective of the study was to analyze the behaviors of women that resulted in menstrually related severe anemia (hemoglobin <5 g/dL) from a single public hospital serving indigent women. This was a retrospective cohort study of all women identified as having been treated at Harbor-UCLA Medical Center for excessive menstruation (International Classification of Diseases, ninth revision, codes 285.9, 6256.2) and hemoglobin values less than 5 g/dL in the 6 years from 2008 to 2013. Approvals were obtained from the Human Subjects and Research Committees. This search identified 271 women with those 2 diagnoses; 122 were excluded because their severe anemia had nonmenstrual causes. The remaining 149 women had 168 episodes with hemoglobin levels below 5 g/dL attributed to chronic excessive menstrual bleeding. Mean age was 41 years (range, 19-55 years). Mean body mass index was 28.9 kg/m(2) (range, 18-57 kg/m(2)); 58.2% were actively bleeding at presentation, and 90.4% reported chronic excessive blood loss. Two thirds recognized heavy bleeding that had persisted for more than 6 months without seeking help. However, 7.8% described their bleeding as normal, and 40.5% had received at least 1 previous transfusion. Mean nadir hemoglobin w...Continue Reading

References

Aug 1, 1984·American Journal of Obstetrics and Gynecology·I S FraserR Markham
Feb 10, 2000·Angiology·D PontilloR Castellani
Jan 22, 2002·The British Journal of Ophthalmology·Christina A Rennie, Declan W Flanagan
Oct 18, 2002·Obstetrics and Gynecology·Isabelle CôtéDavid Cumming
Feb 20, 2003·American Journal of Obstetrics and Gynecology·Isabelle CôtéDavid C Cumming
Jul 5, 1958·Journal of the American Medical Association·A M UNGER, H I NEMUTH
Oct 22, 2004·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Yi-Kong Keung, John Owen
Dec 31, 2004·Obstetrics and Gynecology·Claire S PhilippParvin Saidi
Nov 19, 2005·Internal Medicine·Kazuo Dan
Mar 17, 2007·Fertility and Sterility·Ian S FraserUNKNOWN Writing Group for this Menstrual Agreement Process
May 24, 2007·Acta Obstetricia Et Gynecologica Scandinavica·R HurskainenJ Toivonen
Nov 6, 2007·American Journal of Obstetrics and Gynecology·Maura K WhitemanPolly A Marchbanks
Nov 16, 2007·Journal of Women's Health·Vanessa R Byams
Apr 3, 2008·Journal of Medical Case Reports·Wieland VoigtHans H Wolf
Jul 17, 2008·Vojnosanitetski pregled. Military-medical and pharmaceutical review
Feb 25, 2011·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Malcolm G MunroUNKNOWN FIGO Working Group on Menstrual Disorders
Apr 5, 2011·American Journal of Obstetrics and Gynecology·Griselda Gutierrez, Joy Brotherton
Sep 20, 2011·The Journal of Pediatrics·Shoshana Revel-VilkAriel Revel
Nov 9, 2011·Seminars in Reproductive Medicine·Ian S FraserMalcolm G Munro
Nov 9, 2011·Seminars in Reproductive Medicine·Rohana HaththotuwaIan S Fraser
Jan 4, 2012·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Santiago Palacios
Feb 3, 2012·Journal of Minimally Invasive Gynecology·Elise Hachmann-Nielsen, Martin Rudnicki
Mar 1, 2012·Journal of Women's Health·Jeffrey T JensenMei Sheng Duh
Mar 21, 2012·Journal of Women's Health·Ken MuseTammie L Adomako
Apr 12, 2012·Clinical Medicine Insights. Case Reports·Ramy IbrahimMohammad Zaman
Sep 1, 2012·Women's Health·Andrea S LukesTammie L Adomako
Sep 1, 2012·Case Reports in Neurological Medicine·Preema J MehtaMohankumar Kurukumbi
Oct 31, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·W WangS H O'Brien
Mar 7, 2013·Southern Medical Journal·Robert F Reiss
Jul 11, 2013·European Journal of Gastroenterology & Hepatology·Evangelos VoudoukisIoannis E Koutroubakis
Sep 11, 2013·Journal of Medical Economics·Erika TanakaEdward C Y Wang
Sep 21, 2013·Annals of Hematology·Mariasanta NapolitanoGuglielmo Mariani
Sep 24, 2013·Journal of Child Neurology·Fernando F Corrales-MedinaPedro Mancias
Oct 2, 2013·American Journal of Obstetrics and Gynecology·Kanchan PuriShannon K Laughlin-Tommaso
Oct 11, 2013·Case Reports in Neurological Medicine·H Z Batur CaglayanM Panpalli Ates
Nov 26, 2013·Acta Obstetricia Et Gynecologica Scandinavica·Trine S KarlssonMåns G Edlund
Jan 5, 2014·Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology·Suar Cakı KılıçSema Aylan Gelen
Mar 19, 2014·Headache·Yi-Hsuan DouShuu-Jiun Wang
Oct 2, 2014·The New England Journal of Medicine·Thomas G DeLoughery
Jun 24, 2016·European Journal of Gastroenterology & Hepatology·Dan CarterBenjamin Avidan

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Citations

Nov 28, 2015·Expert Review of Hematology·Sarah-Jo StimpsonMichael R DeBaun
May 7, 2016·American Journal of Hematology·Lisa K HicksWilliam A Wood
Jul 29, 2016·Human Reproduction Update·Jacques Donnez, Marie-Madeleine Dolmans
Dec 21, 2017·F1000Research·Alistair R W Williams
Jun 18, 2020·Nutrients·María Dolores Onieva-ZafraMaría Laura Parra-Fernández
Jun 8, 2016·Contraception and Reproductive Medicine·Anita L NelsonSamuel S Im
Jan 26, 2017·Clinical Obstetrics and Gynecology·Rebecca FlycktTommaso Falcone
Sep 10, 2020·Biology of Reproduction·Sneh M Toprani, Varsha Kelkar Mane
Feb 18, 2021·The New England Journal of Medicine·Ayman Al-HendyElizabeth A Stewart

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