Severe asthma with fungal sensitization: a case report and review of literature

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
Yasser MadaniFurqan Taher

Abstract

There is a substantial body of evidence supporting an association between asthma severity and fungal exposure and sensitization. Fungal allergens are a recognized risk factor for severe asthma. We describe the case of a 44-year-old asthmatic whose asthma control deteriorated after moving to a new flat with walls covered in mould. Allergic bronchopulmonary aspergillosis was excluded. Although sensitization to Candida was demonstrated by a positive Candida-specific radioallergosorbent test, the patient did not entirely satisfy the criteria for a diagnosis of allergic bronchopulmonary candidiasis. The patient's asthma control improved after engaging in a monthly washing regimen of the walls. This case further demonstrates the association between fungal sensitization and asthma severity. The term severe asthma with fungal sensitization has been recently coined to describe this phenomenon.

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Citations

Sep 10, 2013·Journal of Occupational and Environmental Hygiene·Yan Wu, Maosheng Yao
Mar 12, 2011·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Kazuharu TsukiokaKohei Akazawa
Mar 3, 2012·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Livingstone ChishimbaDavid W Denning
May 10, 2011·Pulmonary Pharmacology & Therapeutics·Haruhiko OgawaKoichi Makimura
Mar 23, 2018·Journal of Fungi·Rukumani Devi VelayuthanDavid W Denning

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