PMID: 108923Jan 1, 1979

Severe asthmatic reaction during long-term treatment with disodium cromoglycate powder inhalations

Acta Medica Scandinavica
J Serup

Abstract

Inhalation of inert particles may in susceptible subjects with bronchial asthma result in reflex bronchoconstriction mediated through the vagal nerves. A case of severe asthmatic reaction with bronchial spasm in a 60-year-old man with intrinsic asthma after inhalation of disodium cromoglycate powder (Lomudal) during long-term treatment is reported. The mechanism is considered to be reflexogenic. Because of the variability in individual susceptibility during long-term treatment, inhalation therapy should always be given with close attention to asthmatic exacerbations.

References

May 29, 1976·British Medical Journal·D H Bryant, J Pepys
Jun 1, 1972·Clinical Allergy·J M Smith, Y A Pizzarro
Feb 10, 1968·British Medical Journal·F E SpeizerL B Strang
Mar 1, 1969·Thorax·G M Sterling, J C Batten
Nov 1, 1966·Annals of Internal Medicine·J F Keighley
Jul 1, 1963·Journal of Applied Physiology·J G WIDDICOMBE, J A Nadel
Jul 1, 1962·Journal of Applied Physiology·J G WIDDICOMBEJ A Nadel

Citations

Aug 17, 2000·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·L Ben-Noun
Aug 6, 1983·British Medical Journal·J Rees

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Asthma
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