PMID: 11926573Apr 3, 2002Paper

Severe attack of ulcerative colitis in children: retrospective clinical survey

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Arrigo V BarabinoV Jasonni

Abstract

To obtain clinical data concerning severe attacks of ulcerative colitis in children. A retrospective chart review of 37 children with ulcerative colitis was carried out in order to assess the prevalence, risk factors, timing of presentation, and outcome of severe attacks of ulcerative colitis. A total of 20 severe attacks occurred in 15 out of the 37 patients. No difference in the occurrence of severe attacks was detected in relation to age or disease extent at diagnosis. The mean interval between disease diagnosis and a severe attack was 9.1 months (range 0-30). Of the 20 severe attacks, 11 were resolved with medical treatment in a mean time of 1 1 +/- 4.6 days while 9 out of 20 needed urgent surgery in a mean time of 7.4 +/- 4.8 days. Of 10 out of the 15 patients who recovered from the first attack 4 required colectomy after a mean time of 6.7 months, another 4 are still in remission at a mean period of 40.7 months, one needed elective surgery after 25 months and one was lost to follow-up. Severe attacks of ulcerative colitis had a high prevalence rate [40%); age and disease extent at presentation were not predictors of their occurrence. Approximately half the attacks resolved with medical treatment alone, while the other hal...Continue Reading

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Citations

Feb 20, 2004·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M DapernoA Pera
Feb 22, 2011·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·C Sierra SalinasM D Argos Rodríguez
Nov 18, 2005·Journal of Pediatric Surgery·Girolamo MattioliArrigo V Barabino
Dec 19, 2003·Expert Opinion on Pharmacotherapy·Alan Ronald BremnerRobert Mark Beattie
Dec 5, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Dan TurnerAnne M Griffiths
Jul 21, 2010·Inflammatory Bowel Diseases·Dan Turner, Anne M Griffiths
Jan 13, 2011·The American Journal of Gastroenterology·Dan TurnerUNKNOWN Porto IBD Working Group, European Society of Pediatric Gastroenterology, Hepatology, and Nutrition
Jun 1, 2018·Journal of Pediatric Gastroenterology and Nutrition·Dan TurnerRichard K Russell
Jan 1, 2009·Clinical Reviews in Bone and Mineral Metabolism·Ann PrenticeGail R Goldberg
Jul 10, 2012·Journal of Pediatric Gastroenterology and Nutrition·Dan TurnerUNKNOWN European Society for Paediatric Gastroenterology, Hepatology, and Nutrition
Aug 14, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Francesca PenaginiGian Vincenzo Zuccotti

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