PMID: 2122504Jun 1, 1990Paper

Severe bradycardia and arterial hypotension following the administration of sublingual nitroglycerin

Revista española de cardiología
E Sanz GirgasJ Soler Soler

Abstract

Two patients with coronary artery disease who developed severe bradycardia (less than 40 beats/min) and hypotension (less than 65/...mmHg) in supine position following the administration of sublingual nitroglycerin in the course of an anginal pain are reported. The administration of intravenous atropine sulfate (1-1.5 mg) readily reverted both hypotension and bradycardia. In one patient this complication was observed three times; in this patient sublingual nifedipine (10 mg) was successfully used to treat subsequent anginal crisis.

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