Neonatal vein of Galen malformation complicated by severe cardiac failure is a rare disease. The purpose was to assess the outcome of this life-threatening malformation and identify hemodynamic prognostic factors. Retrospective study. Twenty-four newborns with cardiac failure requiring mechanical ventilation were consecutively admitted from 1986 to 2000. Cardiovascular evaluation including echocardiogram was performed in all cases. Eighteen transarterial shunt occlusions with glue were applied by the same team of three physicians. Twelve babies survived and underwent one endovascular session at least (median age 20 days) with a mean 63 months follow-up. Embolization was not performed in 6 of the 12 nonsurvivors because of severe brain damage or profound hypotension Cardiogenic shock occurred in all nonsurvivors, but also in one long-term survivor (p<0.0001). Echocardiogram showed signs of right ventricular failure, most often in the dead babies (p=0.005). The pulmonary systemic arterial pressure ratio was significantly higher in the nonsurvivor group (p=0.031), and it decreased significantly after the first embolization only in patients who survived (p=0.01). Patent ductus arteriosus and a diastolic aortic reversed-flow were pr...Continue Reading
Neurogenic stunned myocardium after embolization in two children with vein of Galen aneurysmal malformation.
Limitations and technical considerations of endovascular treatment in neonates with high-flow arteriovenous shunts presenting with congestive heart failure: report of two cases
Predicting factors for the follow-up outcome and management decisions in vein of Galen aneurysmal malformations.
A neonate with high-outflow congestive heart failure and pulmonary hypertension due to an intracranial arteriovenous malformation
Endovascular treatment of vein of Galen aneurysmal malformation: management strategy and 21-year experience in Toronto
Vein of Galen aneurysmal malformations: critical analysis of the literature with proposal of a new classification system
Anesthetic management of a neonate with vein of Galen aneurysmal malformations and severe pulmonary hypertension
Vein of Galen aneurysmal malformation and galactosemia in a neonate: a previously unreported association
Outcome and complications of endovascular embolization for vein of Galen malformations: a systematic review and meta-analysis
Pediatric knowledge update: Approach to the management of vein of Galen aneurysmal malformations in neonates
Twin-to-twin transfusion syndrome, vein of galen malformation, and transposition of the great arteries in a pair of monochorionic twins: coincidence or related association?
MR and Diffusion Tensor Imaging of Vein of Galen Aneurysmal Malformation in an Infant Presenting with Spastic Diplegia and Seizures. A Case Report
The natural progression of VGAMs and the need for urgent medical attention: a systematic review and meta-analysis
Hemodynamic disturbances associated with endovascular embolization in newborn infants with vein of Galen malformation
Heart failure caused by VGAM: a lesson for diagnosis and treatment from a case and literature review.
Vein of Galen Malformations: The Texas Children's Hospital Experience in the Modern Endovascular Era
Prenatal diagnosis of aneurysms of the vein of Galen (vena magna cerebri) with conventional sonography, three-dimensional sonography, and magnetic resonance imaging: report of 2 cases
Pulmonary hypertension in an adolescent with end-stage-renal disease-a diagnostic challenge: Answers
Surfactant phospholipids and proteins are increased in fetal sheep with pulmonary hypertension secondary to fetal systemic arteriovenous fistula
Systemic arteriovenous fistula leads to pulmonary artery remodeling and abnormal vasoreactivity in the fetal lamb
Trans-cranial placement of an amplatzer device to control intractable cardiac failure in an infant with a vein of galen anomaly. A case report.
Management and Outcomes of Neonatal Arteriovenous Brain Malformations with Cardiac Failure: A 17 Years' Experience in a Tertiary Referral Center
Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.