Severe chloralose intoxication in a toddler

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
S FedericiK Maréchal

Abstract

We report a case of an accidental intoxication in a 20-month-old boy resulting from the ingestion of a rodenticide containing alpha-chloralose. Three hours after initial admission to the pediatric emergency department for wheezing bronchitis, this patient was readmitted with a clinical presentation of respiratory insufficiency, a Glasgow coma score of 9 alternating with agitation, areflexia and unilateral mydriasis. Parental interview revealed he had episodes of shaking in the afternoon. Chest x-ray showed thoracic distension. Blood investigations, electrocardiogram, cardiac echography, brain CT scan and CSF were normal. Electroencephalography registered slow delta waves 2-3 cycles/min and an aspect of degraded waves and spikes. The patient was transferred to the intensive care unit where he fully recovered within 48 hours. A second parental interview and clinical presentation confirmed an intoxication with a rodenticide containing alpha-chloralose. The late clinical orientation did not allow us to perform a urinanalysis. Clinical association of coma, spontaneous or triggered myoclonias and bronchial hypersecretion are indicative of chloralose intoxication. Presence of specific abnormalities on electroencephalogram and a positi...Continue Reading

References

Jan 1, 1992·Intensive Care Medicine·V DardaineY Furet
May 4, 2004·Annales Françaises D'anesthèsie Et De Rèanimation·E Boyez, P Malherbe
Mar 15, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·S FedericiK Maréchal

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Citations

Mar 18, 2016·Journal of Analytical Toxicology·Marta LeporatiMarco Vincenti
Mar 15, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·S FedericiK Maréchal
Nov 9, 2019·Der Anaesthesist·Sebastian BergrathUllrich Graeven
May 11, 2012·Journal of Analytical Toxicology·E GeraceM Vincenti

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