Severe COVID-19 after liver transplantation, surviving the pitfalls of learning on-the-go: Three case reports

World Journal of Hepatology
Felipe AlconchelPablo Ramírez

Abstract

The novel coronavirus 2019 (COVID-19) pandemic has dramatically transformed the care of the liver transplant patient. In patients who are immunosuppressed and with multiple comorbidities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with increased severity and mortality. The main objective of this report is to communicate our experience in the therapeutic management of SARS-CoV-2 infection in 3 liver transplant patients. Secondly, we stress the management and investigation of the contagious spreading into a liver transplant ward. The patients were two women (aged 61 years and 62 years) and one man (aged 68 years), all of them having recently received a liver transplant. All three patients required intensive care unit admission and invasive mechanical ventilation. Two of them progressed severely until death. The other one, who received tocilizumab, had a good recovery. In the outbreak, the wife of one of the patients and four healthcare professionals involved in their care were also infected. We illustrate in detail the evolution of a nosocomial COVID-19 outbreak in a liver transplant ward. We believe that these findings will contribute to a better understanding of the natural histor...Continue Reading

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Citations

Jul 1, 2021·Nature Reviews. Gastroenterology & Hepatology·Markus F Neurath

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Methods Mentioned

BETA
bronchoalveolar
lavage
bronchoalveolar lavage

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