Severe depressive symptoms and cardiovascular risk in subjects with erectile dysfunction

The Journal of Sexual Medicine
Elisa BandiniMario Maggi

Abstract

Erectile dysfunction (ED) and mood depression are often associated and both are correlated with an increased risk of cardiovascular morbidity and mortality. The aim of the present study is to explore biological and clinical correlates of depressive symptomatology in a sample of men consulting for sexual dysfunction and to verify possible associations between depressive symptoms and incidence of major cardiovascular events (MACE). A consecutive series of 2,303 male patients attending the Outpatient Clinic for sexual dysfunction was retrospectively studied. A subset of the previous sample (N= 1,687) was enrolled in a longitudinal study. All patients were investigated using a Structured Interview on Erectile Dysfunction (SIEDY), composed of 3 scales which explore organic, relational and intra-psychic components of ED. MHQ-D scoring from Middlesex Hospital Questionnaire (MHQ) was used as a putative marker of depressive symptoms. Information on MACE was obtained through the City of Florence Registry Office. We found a positive relationship between MHQ-D score and a progressive impairment in obtaining an erection hard enough for penetration, even after adjusting for confounding factors. Moreover, we observed positive relationships be...Continue Reading

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Citations

Jan 31, 2013·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·H A G Bosinski
Oct 15, 2011·The Journal of Sexual Medicine·Giovanni CoronaFerdinando Fusco
Apr 5, 2011·The Journal of Sexual Medicine·Mario Maggi, Giovanni Corona
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Jan 10, 2012·The Journal of Sexual Medicine·Irwin GoldsteinDonna Schena
May 19, 2012·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Apr 30, 2014·The Journal of Sexual Medicine·Giovanni CoronaMario Maggi
Jan 29, 2013·The Journal of Sexual Medicine·Giovanni Corona, Mario Maggi
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Jun 3, 2011·International Journal of Andrology·A D FisherM Maggi
Mar 21, 2020·Expert Review of Cardiovascular Therapy·G CoronaM Maggi

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