PMID: 11320906Apr 26, 2001Paper

Severe hemolytic anemia and excessive leukocytosis masking mycoplasma pneumonia

Annals of Hematology
F DaxböckW Graninger

Abstract

The formation of cold agglutinins is frequently observed during Mycoplasma pneumoniae infections. Nevertheless, severe hemolysis is exceptional. We report a case of life-threatening hemolytic anemia caused by M. pneumoniae. As the leucocyte count was excessively elevated, the differential diagnosis primarily comprised hematological malignancies. The presence of cold agglutinins indicated the correct diagnosis, which was confirmed by highly elevated levels of both IgG and IgM antibodies to M. pneumoniae and a chest X-ray suggestive of atypical pneumonia. The patient was treated with roxithromycin and showed a favorable recovery within ten days after admission. This case demonstrates that, even in patients with clinically mild pneumonia, M. pneumoniae may be the cause of severe anemia.

Citations

Sep 17, 2009·Journal of Pediatric Hematology/oncology·Orhan GurselAhmet Emin Kurekci
Jan 9, 2007·Journal of Paediatrics and Child Health·Radhakrishnan KottayamRichard J Cohn
Oct 11, 2012·Case Reports in Medicine·Zafer KurugolGuldane Koturoglu
Apr 14, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F LacailleF M Ruemmele
Mar 17, 2010·Journal of Veterinary Emergency and Critical Care·Jane E Sykes
Aug 13, 2003·The Veterinary Clinics of North America. Small Animal Practice·Jane E Sykes
May 11, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F DaxboeckO Assadian
May 7, 2010·Transplant International : Official Journal of the European Society for Organ Transplantation·Gonzalo BotijaGerardo Prieto
Jan 14, 2021·Journal of Clinical Medicine·Aikaterini Voulgaridou, Theodosia A Kalfa
Apr 2, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F DaxboeckC Wenisch

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