Severe hypertension with renal thrombotic microangiopathy: what happened to the usual suspect?

Kidney International
Steven Van Laecke, Wim Van Biesen

Abstract

Patients with atypical hemolytic uremic syndrome (aHUS) and malignant hypertension can both present with concomitant hypertension and thrombotic microangiopathy (TMA), rendering policy decisions complex. Timmermans et al. report that patients with severe hypertension and renal TMA might have unrecognized aHUS with underlying complement abnormalities. Based on this, they assert that all patients presenting with severe hypertension and renal TMA should be evaluated for aHUS. It remains uncertain whether this holds equally true for patients with malignant hypertension and renal TMA.

References

Dec 15, 2004·Hypertension·Bert Jan H van den BornGert A van Montfrans
Jan 13, 2015·Journal of the American Society of Nephrology : JASN·Jamie S ChuaDanielle Cohen
Jan 19, 2016·Journal of the American Society of Hypertension : JASH·Roy O MathewArif Asif
Dec 18, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Ulrich O WenzelHeimo Ehmke
Feb 12, 2017·Kidney International·Sjoerd A M E G TimmermansUNKNOWN Limburg Renal Registry

❮ Previous
Next ❯

Citations

Oct 19, 2017·Clinical Journal of the American Society of Nephrology : CJASN·Vicky BrocklebankDavid Kavanagh
Mar 14, 2019·Current Opinion in Nephrology and Hypertension·Ramy M HannaRichard Burwick
Nov 18, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Christopher P LarsenRandolph A Hennigar
Jun 26, 2020·British Journal of Pharmacology·Ulrich O WenzelMarlies Bode
Dec 29, 2020·British Journal of Community Nursing·Ehsan Khan
Dec 11, 2020·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fadi FakhouriVéronique Frémeaux-Bacchi
Oct 30, 2021·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Ludwig HaydockPaul Isenring

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
M BurdeaG Dobrescu
Clinical Journal of the American Society of Nephrology : CJASN
David KavanaghJohn P Atkinson
Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
Yeşim OymakCanan Vergin
© 2022 Meta ULC. All rights reserved