Severe hypertriglyceridemia: an indication for apheresis?

Atherosclerosis. Supplements
Nils Ewald, Hans-Ulrich Kloer

Abstract

Severe hypertriglyceridemia is associated with a number of severe complications such as acute pancreatitis. Rapid lowering of excessively elevated triglyceride (TG) levels is therefore a primary medical goal in these patients. According to previous reports, immediate apheretic treatment might be an interesting option in order to rapidly lower excessively elevated TG levels. A review of the current available literature was therefore conducted in order to provide an overview of the present data on apheretic treatment for patients with severe hypertriglyceridemia. A single session of plasmapheresis proofs capable of lowering TG levels by up to 70%, producing clear clinical and laboratory improval. The best clinical benefit concerning reduction in morbitity and mortality can be achieved when apheresis is used as early as possible. Even repetitive use of apheresis is reported. There is controversy on technical details, such as different apheresis techniques (plasma exchange versus double-membrane filtration), slightly favoring plasma exchange. In patients with severe hypertriglyceridemia plasmapheresis seems to be a safe and useful tool in rapidly lowering excessively elevated TG levels. Apheresis can be used to rapidly decrease tri...Continue Reading

References

Sep 1, 1971·Annals of Internal Medicine·D S Fredrickson
Jul 31, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·A LennertzT Bosch
Nov 17, 2004·The American Journal of the Medical Sciences·Said B Iskandar, Kenneth E Olive
Jun 12, 2008·Annals of Nutrition & Metabolism·Annette HauenschildPhilip D Hardt
Jun 27, 2008·Pancreas·Célia Lloret LinaresEric Bruckert

❮ Previous
Next ❯

Citations

Mar 13, 2013·Archives of Gynecology and Obstetrics·Rafet BasarNese Colak Ozbey
Jul 17, 2013·Journal of Cardiovascular Translational Research·Richard G LeeRosanne M Crooke
Jul 23, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Francesco SbranaTiziana Sampietro
Mar 26, 2013·Nutrients·Amanda Brahm, Robert A Hegele
Apr 3, 2014·Gastroenterología y hepatología·María Isabel Ostabal Artigas
Jan 19, 2012·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Radka IvanovaPedro Valdivielso
Apr 5, 2011·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Katty Manrique FrancoAdela Rovira Loscos
Apr 9, 2015·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Heike ZeitlerChristian P Strassburg
Apr 5, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Ornella GuardamagnaFrancesca Abello
Feb 6, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Dehua GongZhihong Liu
Sep 10, 2013·European Journal of Internal Medicine·A Ramírez-BuenoP Valdivielso
Sep 10, 2015·Journal of Clinical Lipidology·Isabel Galán CarrilloFernando Anaya
Sep 8, 2015·Journal of Clinical Lipidology·Amy S Shah, Don P Wilson
May 20, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Qiuxiang XuZhenyu Zhang
Mar 4, 2015·Nature Reviews. Endocrinology·Amanda J Brahm, Robert A Hegele
Aug 16, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Efstathios P PapadakisVasilios Karagiannis
Feb 18, 2015·Clinical Research in Cardiology Supplements·P GrützmacherB Öhm
Dec 21, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·G DucarmeP Hammel
Sep 3, 2017·Pediatrics in Review·Badhma ValaiyapathiAmbika P Ashraf
Aug 3, 2013·Critical Care Nurse·Gilbert SedaMassoud Daheshia
Jul 28, 2020·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Pedram AhmadpoorOlivier Moranne
Jun 21, 2018·Clinical Journal of Gastroenterology·Prashanth RawlaVinaya Gaduputi
Jul 29, 2016·Journal of Atherosclerosis and Thrombosis·Tsuyoshi YamamotoMariko Harada-Shiba
Oct 25, 2020·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Gulay Simsek Bagirİlknur Kozanoglu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Research in Cardiology Supplements
Nils Ewald, Hans-Ulrich Kloer
Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis
A LennertzT Bosch
Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
C StefanuttiG Labbadia
Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Gurhan KadikoyluZahit Bolaman
© 2021 Meta ULC. All rights reserved