PMID: 2124781Dec 1, 1990Paper

Severe hypertriglyceridemia in diabetic ketosis

The American Journal of the Medical Sciences
M Fulop, H Eder

Abstract

In order to learn whether patients with diabetic ketosis who had very severe hypertriglyceridemia had underlying genetic hyperlipidemia, the authors measured plasma lipids in 211 episodes. They report the findings in the 15 patients who had initial plasma triglyceride concentrations above 11.3 mmol/L (1,000 mg/dL). These patients were detected during a prospective study of 155 episodes of ketoacidosis and 56 episodes of ketosis. Eleven of the 15 patients had definite or probable insulin-dependent diabetes mellitus (IDDM), but eight of the 15 were not acidemic despite their ketosis. Twelve of the 15 patients (80%) were men, a far higher percentage of men than the 53.6% in the base population of 211 episodes. Plasma triglyceride concentrations returned to normal levels either during the acute episode (seven cases) or well within a year (two more cases) in most of the patients. From that and other considerations, the authors infer that at least ten, and perhaps 12 of the 15 patients did not have an underlying genetic hyperlipidemia contributing to their original severe hypertriglyceridemia. That contrasts with the findings of others who reported that most patients with severe hypertriglyceridemia associated with noninsulin-depende...Continue Reading

References

Oct 1, 1975·Metabolism: Clinical and Experimental·J D BrunzellE L Bierman
Sep 1, 1989·Archives of Internal Medicine·M Fulop, H A Eder
May 1, 1981·Diabetes Care·A ChaitJ D Brunzell

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Citations

Dec 31, 1993·Clinica Chimica Acta; International Journal of Clinical Chemistry·J L ReverterA Sanmartí
Oct 2, 2013·Indian Journal of Endocrinology and Metabolism·Sunil Kumar KotaKirtikumar D Modi
Feb 24, 2016·Case Reports in Endocrinology·Tansit SaengkaewVichit Supornsilchai
Jan 1, 1992·Baillière's Clinical Endocrinology and Metabolism·W Berger, U Keller
Feb 17, 2015·Journal of Forensic Sciences·Chong ZhouRoger W Byard
Jul 26, 2017·Journal of Pediatric Endocrinology & Metabolism : JPEM·Tyler FickRohan K Henry
Oct 29, 2000·The American Journal of Gastroenterology·S NairC S Pitchumoni
Nov 6, 2018·Endocrine Journal·Satoko TsuchiyaHideki Katagiri
Sep 3, 2010·Journal of Korean Medical Science·Suk Jae HahnKyoung-Ah Kim
Jul 11, 2018·Clinical Case Reports·Christel Keefe, Sarah Lawson
Feb 23, 2019·Paediatrics & Child Health·Brianna McKelvie, Robert Stein
Nov 28, 2009·Arquivos brasileiros de endocrinologia e metabologia·Giancarlo LucchettiVinicius Marcus Battistella
Aug 19, 2014·Diabetic Medicine : a Journal of the British Diabetic Association·A RadhakuttyM P Doogue
Oct 3, 2020·Pediatrics in Review·Chris NovakJessica Foulds
Feb 7, 2019·Case Reports in Endocrinology·Fatima Zahra ZaherNawal Elansari
May 20, 2021·Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis·Clara ViñalsEmilio Ortega

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