PMID: 5920755Sep 9, 1966

Severe impairment of heat-induced saliva-spreading in rats recovered from lateral hypothalamic lesions

F R Hainsworth, A N Epstein


A method has been devised to record saliva-spreading on fur and skin by rats in the heat. Normal males and females increase saliva-spreading with increasing ambient temperatures. Rats recovered from lateral hypothalamic lesions do not spread saliva in the heat, confirming the inference drawn from studies of their drinking behavior that their saliva production is severely impaired. Recovered lateral rats do produce saliva when injected with pilocarpine. The failure to salivate is, therefore, a result of the lateral hypothalamic lesions and is not due to an incompetence of the glands.


Jul 1, 1992·Developmental Psychobiology·E M Blass
Aug 1, 1969·Electroencephalography and Clinical Neurophysiology·C S Rebert, D A Irwin
Sep 1, 1978·Physiology & Behavior·T SchallertJ J Braun
Jun 1, 1980·Physiology & Behavior·S W Corbett, R E Keesey
Jan 1, 1986·Physiology & Behavior·R Refinetti, H J Carlisle
Jan 1, 1996·Neuroscience and Biobehavioral Reviews·L L BERNARDIS, L L Bellinger
Nov 1, 1974·Comparative Biochemistry and Physiology. A, Comparative Physiology·A D NeedhamJ R Hales
Apr 6, 1999·Pharmacology & Therapeutics·H Izumi
Sep 21, 2002·Brain Research Bulletin·A RenziJ V Menani
Jun 26, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·P K Phillips, J E Heath
Jun 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·J W HoladayC H Li
May 27, 2016·Temperature : Multidisciplinary Biomedical Journal·Maria Camila AlmeidaDaniel Carneiro Carrettiero
Nov 1, 1971·The Journal of Experimental Zoology·R V Clark
Jan 1, 1969·Toxicology and Applied Pharmacology·T Skobba, T S Miya
May 21, 2013·Archives of Oral Biology·J P PrestifilippoJ Fernandez-Solari
May 19, 2009·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J Fernandez-SolariJ C Elverdin
Jul 8, 2003·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·W A SaadJ Antunes Rodrigues
Jan 15, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Douglas G Whyte, Alan Kim Johnson
Nov 5, 1976·Pflügers Archiv : European journal of physiology·M CabanacL J Poirier
Oct 26, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M L MathaiM J McKinley

Related Concepts

Organum Vasculosum Laminae Terminalis
Secretion of Saliva

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.