PMID: 3522306Jun 1, 1986Paper

Severe intrauterine growth retardation; assessment of its origin from fetal arterial flow velocity waveforms

European Journal of Obstetrics, Gynecology, and Reproductive Biology
J W WladimiroffA Reuss

Abstract

Doppler blood flow velocity waveforms in the umbilical artery and fetal internal carotid artery were recorded in a total of 10 patients with severe intrauterine growth retardation (IUGR) and marked oligohydramnios to establish a fetal or utero-placental origin of IUGR. Gestational age varied between 28 and 37 wk. Negative maternal serology ruled out fetal infections. In six patients, IUGR was associated with abnormal flow velocity waveforms, indicating utero-placental insufficiency. Following delivery, these infants showed no structural defects; moderate to marked placental infarction was documented in 4 out of 6 cases. In the remaining four patients, IUGR was associated with normal flow velocity waveforms, suggesting a fetal origin of the IUGR. Following delivery, all four infants revealed structural defects, only one of which was diagnosed prenatally. Twice an abnormal karyotype was the underlying cause. There was no placental infarction. These preliminary data suggest that combined recording of the flow velocity waveform in the above-mentioned vessels may provide valuable additional information as to the cause of IUGR and as such be helpful in determining obstetric management.

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Citations

Jun 1, 1992·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M ShinodaY Suzuki
Jan 1, 1991·Seminars in Roentgenology·E G Grant
Jun 24, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Dimitrios KassanosGeorge Creatsas
Jun 1, 1994·British Journal of Obstetrics and Gynaecology·M J NoordamJ W Wladimiroff
Jan 1, 1993·Journal of Perinatal Medicine·F KainerJ W Dudenhausen
Feb 1, 1990·American Journal of Obstetrics and Gynecology·J C Veille, I Cohen
May 5, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Akira MoriChihiro Tsutsui
Mar 1, 1988·Baillière's Clinical Obstetrics and Gynaecology·K Marsal
Jan 21, 2006·The Journal of Pediatrics·Mori Akira, Saburi Yoshiyuki
Sep 12, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J C TanisC M Bilardo
Jul 20, 2017·Journal of Developmental Origins of Health and Disease·C W KuzawaT W McDade
Sep 1, 1988·Journal of Clinical Ultrasound : JCU·P KirkinenA Huch

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