Severe malaria in immigrant haematological patient

IDCases
R Vázquez-SánchezT Molina-García

Abstract

Severe malaria is a life-threatening condition caused by Plasmodium falciparum. Rupture of red blood cells when merozoites release to the bloodstream is responsible for the clinical manifestations, febrile fever reaching 39 °C, and other unspecific symptoms. P. falciparum is considered as the worst form of malaria. Moreover, this species has cytoadherence to red blood cells. This can lead to an organic dysfunction. People coming from hyper endemic areas have developed a partial immunity, but immunodepressed people are a group with a greater risk. Due to the high mortality rate associated to this disease, early diagnosis and a prompt treatment implementation are essential. However, the missed or delayed diagnosis is one of the major reasons of reaching a severe malaria disease. This case reflects the complexity of the diagnosis in an immigrant and immunodepressed patient with a haematological neoplasm with a severe infection by P. falciparum due to the unspecified symptoms and the overlapping of the same.

References

Nov 22, 2005·Lancet Neurology·Richard IdroCharles R J C Newton
Jan 23, 2010·Biologicals : Journal of the International Association of Biological Standardization·UNKNOWN WHO
Sep 19, 2012·Malaria Journal·Helena H AsklingUNKNOWN European Society for Clinical Microbiology and Infectious Diseases Study Group on Clinical Parasitology
Sep 13, 2014·Tropical Medicine & International Health : TM & IH

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Methods Mentioned

BETA
biopsy

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