Severe morbidity and mortality risk from malaria in the United States, 1985-2011

Open Forum Infectious Diseases
Jimee HwangJ K Baird

Abstract

Recent reports of Plasmodium vivax associated with severe syndromes and mortality from malaria endemic areas questions the "benign" course of non-falciparum malarias. We retrospectively analyzed data from patients reported to the US Centers for Disease Control and Prevention with a diagnosis of malaria parasite single-species infection between 1985 and 2011. Patients classified as having severe illness were further classified according to outcome (survival versus death) and clinical syndrome. Among all cases, .9% of Plasmodium falciparum cases resulted in death and 9.3% were classified as severe, whereas .09% of P. vivax cases resulted in death and 1.3% were classified as severe. The odds ratios for severe illness among 15 272 diagnoses of P. falciparum relative to patients diagnosed with P. vivax (n = 12 152), Plasmodium malariae (n = 1254), or Plasmodium ovale (n = 903) was 7.5, 5.7, and 5.0, respectively (P < .0001 for all); in contrast, the corresponding odds ratios for death among those severely ill was 1.6, 1.1, and .8 (P > .1 for all), respectively. Compared with P. vivax (n = 163), the odds of P. falciparum cases classified as severely ill (n = 1416) were 1.9 (P = .0006), .5 (P = .001), and 1.3 times (P = .1) as likely ...Continue Reading

References

Dec 10, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E Schwartz, G Regev-Yochay
Oct 17, 2003·The New England Journal of Medicine·Thomas E Wellems, Louis H Miller
Oct 17, 2003·The New England Journal of Medicine·Eli SchwartzMartin Cetron
Feb 12, 2005·Emerging Infectious Diseases·Dhanpat K KocharAshis Das
Apr 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jeanne Rini PoespoprodjoRic N Price
Jan 13, 2009·Clinical Microbiology Reviews·Denise L DoolanJ Kevin Baird
May 15, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jeanne R PoespoprodjoRic N Price
Jun 16, 2009·Journal of Public Health Management and Practice : JPHMP·Jimee HwangPaul Arguin
Jul 3, 2009·Current Opinion in Infectious Diseases·Ric N PriceNicholas M Anstey
Jan 15, 2010·Malaria Journal·Bruno B AndradeManoel Barral-Netto
Jun 22, 2010·PLoS Medicine·Simon I HayRobert W Snow
Aug 7, 2010·PLoS Neglected Tropical Diseases·Carlos A GuerraSimon I Hay
Nov 3, 2010·The American Journal of Tropical Medicine and Hygiene·Dhanpat Kumar KocharAshish Das
Dec 7, 2011·The American Journal of Tropical Medicine and Hygiene·Laura C SteinhardtPaul M Arguin
Mar 15, 2012·Current Infectious Disease Reports·J Kevin Baird
Sep 13, 2012·PLoS Neglected Tropical Diseases·Peter W GethingSimon I Hay
Jan 9, 2013·Clinical Microbiology Reviews·J Kevin Baird
Apr 5, 2013·Clinical Microbiology Reviews·Balbir Singh, Cyrus Daneshvar
Apr 27, 2013·Chest·Earl S FordWayne H Giles
Jun 22, 2014·Health Promotion Practice·Cynthia Baur, Christine Prue

❮ Previous
Next ❯

Citations

Nov 15, 2013·The Journal of Parasitology·Will K Reeves, Amy L Bettano
Feb 3, 2016·Enfermedades infecciosas y microbiología clínica·Gerardo Rojo-Marcos, Juan Cuadros-González
Nov 28, 2015·Trends in Molecular Medicine·Jean Popovici, Didier Ménard
Jul 20, 2017·The American Journal of Tropical Medicine and Hygiene·Fernando ValMarcus Vinícius Guimarães Lacerda
Nov 1, 2018·Journal of Travel Medicine·J Kevin Baird
Sep 9, 2017·Tropical Diseases, Travel Medicine and Vaccines·J Kevin Baird
May 16, 2018·The American Journal of Tropical Medicine and Hygiene·Andrew A LoverRic N Price
Jul 19, 2017·The American Journal of Tropical Medicine and Hygiene·Diana KhuuFrank J Sorvillo
Sep 29, 2020·Frontiers in Immunology·Tatiana Almeida Pádua, Mariana Conceição Souza
Oct 9, 2020·PLoS Computational Biology·Bridget S Penman, Sylvain Gandon
Dec 23, 2017·Infectious Disease Clinics of North America·Natasha M Kafai, Audrey R Odom John
May 23, 2021·The Journal of Antimicrobial Chemotherapy·Laurent DembeleAbdoulaye A Djimde

❮ Previous
Next ❯

Software Mentioned

SAS
NMSS

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Related Papers

The American Journal of Tropical Medicine and Hygiene
Gerardo Rojo-MarcosRaúl de Pablo-Sánchez
Transactions of the Royal Society of Tropical Medicine and Hygiene
P DruilheJ Periês
Przegla̧d lekarski
Agnieszka ZdrodowskaMaciej Kondrusik
© 2022 Meta ULC. All rights reserved