Severe personality changes after unilateral left paramedian thalamic infarct

European Neurology
Toshio FukutakeYoshihiro Ueki

Abstract

Personality changes are not uncommon after paramedian thalamic infarction, but usually bilateral or relatively large lesions, often complicated by other neurological or neuropsychological deficits, are present. 'Pure' cases of unilateral lesions are extremely rare. We report that a right-handed, 48-year-old man, who was hypertensive and diabetic but had no prior psychiatric history, developed severe personality changes and a frontal-like syndrome after recovery from acute-onset impairment of consciousness at the age of 43. Other neurological and neuropsychological disturbances, especially verbal and visual amnesia, were unremarkable. MRI showed a very small infarct in the left paramedian area of the thalamus, mainly involving the dorsomedial nucleus.

Citations

Oct 30, 2004·The International Journal of Neuroscience·Marcello Spinella
Jan 28, 2009·Brain Injury : [BI]·Simon L CollinsonJeffrey V Rosenfeld
Jan 25, 2011·Neuropsychologia·Giovanni Augusto CarlesimoCarlo Caltagirone
Nov 30, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Lieve De WittePeter Mariën
Dec 1, 2007·Stroke; a Journal of Cerebral Circulation·Dirk M HermannClaudio L Bassetti

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