Severe post-renal acute kidney injury, post-obstructive diuresis and renal recovery

BJU International
Aïcha HamdiVincent Das

Abstract

Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? The pathophysiology of post-renal acute kidney injury (PR-AKI), i.e. caused by urinary tract obstruction, has been extensively studied in animal models but clinical studies on this subject are outdated, and/or have focused on the mechanisms of 'post-obstructive diuresis' (POD), a potentially life-threatening polyuria that can develop after the release of obstruction. In severe PR-AKI, the risk of occurrence of POD is high. POD occurrence predicts renal recovery without the persistence of severe chronic kidney failure. In the present study, the occurrence of POD and the persistence of chronic renal sequelae could be predicted early from clinical variables at admission before the release of obstruction. • To identify predictors of post-obstructive diuresis (POD) occurrence or severe chronic renal failure (CRF) persistence after the release of urinary tract obstruction in the setting of post-renal acute kidney injury (PR-AKI). • Bi-centre retrospective observational study of all patients with PR-AKI treated in two intensive care units (ICUs) from 1998 to 2010. • Clinical, biological and imaging characteristics on admiss...Continue Reading

References

Feb 1, 1975·The Journal of Urology·L J PetersonJ F Glenn
Feb 1, 1976·The Journal of Urology·S R Shapiro, A H Bennett
Apr 1, 1989·The Journal of Urology·I Sarmina, M I Resnick
Jul 1, 1989·The Journal of Urology·A L LeahyJ M Fitzpatrick
Feb 1, 1985·British Journal of Urology·M C Bishop
Dec 1, 1970·Journal of the American Geriatrics Society·R G Narins
Jun 9, 1966·The New England Journal of Medicine·F P MuldowneyR Freaney
Jan 1, 1967·The Journal of Urology·V L Robards, G Ross
Nov 1, 1973·The Journal of Urology·S S Howards
Jan 1, 1967·Annals of Internal Medicine·S G MassryG E Schreiner
Feb 1, 1983·Kidney International·S Klahr
Nov 1, 1980·Radiology·J G McAfeeJ P O'Callaghan
Apr 14, 1997·Archives of Internal Medicine·J R OsterJ M Diego
Apr 16, 1998·QJM : Monthly Journal of the Association of Physicians·I H KhanA M Macleod
Jun 29, 2000·Intensive Care Medicine·K AkpossoJ D Sraer
Mar 1, 1956·The American Journal of Physiology·W S KERR
Oct 1, 1957·The American Journal of Medicine·N S BRICKERJ H HOLMES
Aug 1, 1964·The American Journal of Medicine·M H WITTEW HOLLANDER
Aug 18, 2004·Critical Care : the Official Journal of the Critical Care Forum·Rinaldo BellomoUNKNOWN Acute Dialysis Quality Initiative workgroup
Jan 1, 1950·Cancer·W J YOUDEN
Feb 1, 2005·Lancet·Norbert LameireRaymond Vanholder
Mar 9, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Belda Dursun, Charles L Edelstein
Sep 22, 2006·Kidney International·R L Chevalier
May 15, 2007·The Journal of Urology·Lih-Ming WongAlexander G Pitman
Apr 3, 2009·Kidney International·Robert L ChevalierBarbara A Thornhill

❮ Previous
Next ❯

Citations

Jul 9, 2014·Nature Reviews. Urology·Marcus J DrakeDominika A Bijos
Apr 11, 2013·Critical Care Research and Practice·James CaseAkram Khan
Nov 23, 2016·Journal of the American Veterinary Medical Association·William T N CulpKenneth J Drobatz
Dec 23, 2015·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Nicolas HoarauPierre Bigot
May 26, 2020·Scandinavian Journal of Urology·Lisbeth Roesen LeinumNessn Azawi
Nov 22, 2019·World Journal of Urology·Vincent De ConinckOlivier Traxer
Oct 20, 2018·International Journal of Molecular Sciences·Keiko HosohataKazunori Iwanaga
Jul 10, 2019·British Journal of Hospital Medicine·Sayani KharaDeepak Batura
Apr 10, 2019·Deutsches Ärzteblatt International·Mark Dominik AlscherMartin K Kuhlmann
Apr 11, 2020·Qatar Medical Journal·Nissar ShaikhAbdulla Ansari

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.