PMID: 11967509Apr 23, 2002Paper

Severe preeclampsia at <25 weeks of gestation: maternal and neonatal outcomes

American Journal of Obstetrics and Gynecology
Sheri M JenkinsJohn C Hauth

Abstract

The purpose of this study was to determine maternal and neonatal outcomes of women who were delivered because of severe preeclampsia before 25 weeks of gestation. We used a computerized database to identify 3800 women with preeclampsia among 35,937 deliveries from 1991 to 1997. Of these, 39 women (1%) with severe preeclampsia were delivered before 25 weeks of gestation. We abstracted outcomes in these women and their newborns. All 39 women had severe preeclampsia as defined by clinical and/or laboratory criteria. Thirty-three of the 39 women had severe-range hypertension. Twenty-one women (54%) experienced morbidity that included abruptio placentae (n = 5), HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome (n = 9), renal insufficiency (n = 5), and eclampsia (n = 3). No women required dialysis or intensive care unit admission, and none of the women died. All maternal morbidities reversed after delivery. Twenty-two infants (55%) were live-born. Only 4 infants (10%) survived, all with severe handicaps. In women with severe preeclampsia before 25 weeks of gestation, delivery is associated with minimal short-term maternal morbidities, although neonatal morbidity and death are appreciable.

References

Sep 1, 1990·American Journal of Obstetrics and Gynecology·B M SibaiM Moretti
May 1, 1985·American Journal of Obstetrics and Gynecology·B M SibaiG D Anderson

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Citations

Aug 9, 2011·Vascular Health and Risk Management·Jennifer UzanJean-Marc Ayoubi
Feb 21, 2008·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ching-Ming LiuShuenn-Dyh Chang
Mar 13, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kimberly HannamJon H Tobias
Sep 7, 2006·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Astrid BuddenLesley McCowan
Aug 27, 2013·American Journal of Obstetrics and Gynecology·Sarka Lisonkova, K S Joseph
Nov 11, 2011·American Journal of Obstetrics and Gynecology·UNKNOWN Publications Committee, Society for Maternal-Fetal Medicine, Baha M Sibai
Jun 6, 2007·American Journal of Obstetrics and Gynecology·Baha M Sibai, John R Barton
Sep 11, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Leonoor Van EerdenAntoinette C Bolte
May 20, 2014·Seminars in Perinatology·Cande V Ananth, Alexander M Friedman
Nov 14, 2017·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Karolina Panek-LaszczyńskaZbigniew Szewczuk
May 4, 2004·Obstetrics and Gynecology·Mette Ree HoltheTorstein Lyberg
Jul 2, 2008·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Yapo BrouhYves Yapobi
Mar 12, 2009·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·L A MageeP von Dadelszen
Sep 4, 2008·Public Health Reports·Daniel R ThompsonMary Beth Zeni
Sep 21, 2017·Case Reports in Obstetrics and Gynecology·Peter KascakRadovan Gajdosik

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