Severe retinopathy of prematurity: longitudinal observation of disease and screening implications

Eye
Anna L EllsA Ingram

Abstract

To test the effectiveness of our Canadian retinopathy of prematurity (ROP) screening guidelines as applied to high-risk premature infants. Retrospective longitudinal cohort study. A total of 969 infants were examined longitudinally between 1991 and 2000 and 46 of these infants screened were treated for severe ROP. Data from weekly ROP screening examination results were collected from a geographical area and analysed. The average incidence of severe ROP requiring treatment in the population of premature infants eligible for screening was 48.3 per 1000. In all, 46 infants were treated in this cohort. The mean gestational age (GA) was 25.5 weeks of age and the mean birth weight was 750 g. The mean chronological age (CA) and postmenstrual age (PMA) at the time of first screening was 36 days and 30.7 weeks, respectively. The first identification of any ROP in this group was at a mean CA 60 days and PMA of 34.1 weeks. The mean CA and PMA of the first observation of stage 3 were 74 days and 36.3 weeks. The mean CA and PMA at the time of treatment were 86 days and 37.7 week. Our observations and analysis indicate the following ROP screening recommendations: infants of 28 weeks of GA or less, infants with a GA between 28 weeks and 30 we...Continue Reading

References

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Citations

Apr 24, 2007·International Ophthalmology Clinics·Stephen R SmithEdward A Ryan
Feb 14, 2014·PloS One·Alejandro Pérez-MuñuzuriJosé María Fraga-Bermúdez
Sep 3, 2011·Middle East African Journal of Ophthalmology·Kakarla V ChalamRavi Radhakrishnan
Jun 13, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Gloria Isaza, Sourabh Arora
Dec 12, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Vasudha GuptaKourosh Sabri
May 31, 2013·Clinics in Perinatology·Clare M WilsonAlistair R Fielder
Jan 18, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Shu Fen HoT Marshall
Feb 12, 2009·Retina·UNKNOWN Photographic Screening for Retinopathy of Prematurity (Photo-ROP) Cooperative Group
Dec 2, 2011·Paediatrics & Child Health·Al Jefferies
Sep 16, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ali Riza Cenk CelebiAhmet Yagmur Bas

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