PMID: 2510780Jan 1, 1989Paper

Severed nerve stumps around a laser-irradiated locus in the deep muscular plexus of the guinea-pig small intestine

Archives of Histology and Cytology
S KobayashiT Nishisaka

Abstract

Small foci of photocoagulation necrosis (diameter about 0.5 mm) were produced in the wall of the guinea-pig small intestine by argon laser irradiation applied to the serosal surface. Features of the nerve elements around the necrotic masses were examined by immunocytochemistry, scanning electron microscopy, and transmission electron microscopy. The severed ends of nerve strands were examined at various intervals from 10 to 60 h after the laser irradiation, and the acute cytological responses of the nerve terminals, glial cells and connective tissue cells were studied. The laser irradiated foci in the deep muscular plexus (plexus muscularis profundus: CAJAL, 1911) had concentric configuration: 1) central necrotic area, 2) inner transitional zone, 3) outer transitional zone, and 4) normal area. In the necrotic area, there were inflammatory cells such as neutrophile leukocytes and macrophages. Contours of the smooth muscle cells and nerve strands were well preserved in spite of the damage to their subcellular structures. In the inner transitional area, individual nerve fibers gathered to form bundles. Some of these nerve bundles were devoid of a glial cell framework. In the outer transitional zone, there were swollen nerve termina...Continue Reading

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