Severity and duration of diabetic foot ulcer (DFU) before seeking care as predictors of healing time: A retrospective cohort study

PloS One
Hilde Smith-StrømBerit Rokne

Abstract

To investigate whether A) duration of ulcer before start of treatment in specialist health care, and B) severity of ulcer according to University of Texas classification system (UT) at start of treatment (baseline), are independent predictors of healing time. This retrospective cohort study, based on electronic medical record data, included 105 patients from two outpatient clinics in Western Norway with a new diabetic foot ulcer during 2009-2011. The associations of duration of ulcer and ulcer severity with healing time were assessed using cumulative incidence curves and subdistribution hazard ratio estimated using competing risk regression with adjustment for potential confounders. Of the 105 participants, 45.7% achieved ulcer healing, 36.2% underwent amputations, 9.5% died before ulcer healing and 8.5% were lost to follow-up. Patients who were referred to specialist health care by a general practitioner ≥ 52 days after ulcer onset had a 58% (SHR 0.42, CI 0.18-0.98) decreased healing rate compared to patients who were referred earlier, in the adjusted model. High severity (grade 2/3, stage C/D) according to the UT classification system was associated with a decreased healing rate compared to low severity (grade1, stage A/B or ...Continue Reading

References

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Citations

Apr 27, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·C J W Pankhurst, M E Edmonds
Mar 6, 2019·Journal of Wound Care·Leanne AtkinWilliam Tettelbach
Apr 17, 2019·JMIR MHealth and UHealth·David WallaceKaren Michelle Cross
Jun 6, 2019·Journal of Wound Care·José Luis Lázaro-MartínezAlberto Piaggesi
Nov 21, 2019·The International Journal of Lower Extremity Wounds·Kaissar Yammine, Chahine Assi
Aug 17, 2019·International Wound Journal·Maryam Mohammad ZadehAnne-Margreet van Dishoeck
Mar 22, 2018·Diabetes Care·William J JeffcoateAndrew J M Boulton
Jun 18, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Milad JalilianSajad Oubari
Dec 20, 2018·Foot & Ankle Specialist·Kaissar YammineChahine Assi
Dec 4, 2019·Journal of Foot and Ankle Research·Laurens ManningJens C Ritter
Nov 26, 2020·International Wound Journal·Jérôme PatryClermont E Dionne
Nov 29, 2020·International Journal of Nursing Studies·Ma'en Zaid Abu-QamarLisa Whitehead
Feb 11, 2021·Plastic and Reconstructive Surgery. Global Open·Paige K DekkerKenneth L Fan
Nov 20, 2020·Journal of Family Medicine and Primary Care·Shruti BarnwalPoonam Yadav
Nov 9, 2020·Canadian Journal of Diabetes·Cynthia FournierMarie-Marthe Thibeault
Apr 3, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Anne-Sophie MarietJean-Michel Petit
Jun 1, 2021·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Thomas E SerenaMarissa J Carter
Oct 14, 2021·Journal of Wound Care·Benjamin BouilletRaju Ahluwalia
Oct 14, 2021·Journal of Wound Care·Benjamin BouilletJosé Luis Lázaro-Martínez

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Methods Mentioned

BETA
amputation
artery
percutaneous transluminal angiography

Software Mentioned

Stata
Eurodiale
SPSS

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