Severity of disease as main predictor for mortality in patients with pyogenic liver abscess

American Journal of Surgery
Shiuan-Chih ChenMeng-Chih Lee

Abstract

The purpose of this study was to explore the relationship between severity of illness at admission and mortality of patients with pyogenic liver abscess (PLA). Medical records from 298 PLA patients > or =18 years old were reviewed. Severity of illness at admission was evaluated with the Acute Physiology and Chronic Health Evaluation (APACHE) II and the simplified acute physiology score (SAPS) II scoring systems. Stepwise logistic regression and receiver-operating-characteristic curve analyses were performed. The case-fatality rate was 10%. Multivariate analysis showed that APACHE II (P = .0004), SAPS II (P = .0008), the presence of gas-forming abscess (P <.0001), and the presence of anaerobic infection (P <.0001) all were associated with mortality. The area under the receiver-operating-characteristic curve was .884 (95% confidence interval .842 to .918) for APACHE II and .857 (95% confidence interval .812 to .895) for SAPS II, which were not significantly different (P = .490). The optimal cutoff APACHE II value of > or =15 had a sensitivity of 77% and a specificity of 92%, with a 20.3-fold risk of mortality (P <.0001). The SAPS II cutoff value of > or =28 had a sensitivity of 74% and a specificity of 82%, with a 7.2-fold risk o...Continue Reading

References

Mar 1, 1979·Reviews of Infectious Diseases·D L Kasper
May 1, 1991·World Journal of Surgery·K T LeeC G Ker
Jan 1, 1990·Reviews of Infectious Diseases·A B OnderdonkD L Kasper
Jul 27, 1989·The New England Journal of Medicine·B Styrt, Sherwood Gorbach
Aug 1, 1985·Journal of Clinical Pathology·J J Finlay-Jones, M Reznikov
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Mar 1, 1984·Reviews of Infectious Diseases·T Hofstad
Mar 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J CarrataláF Gudiol
Nov 1, 1994·World Journal of Surgery·H J MischingerE Deu
Dec 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M E FalagasD R Snydman
Jun 24, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H WangH H Lin
Sep 15, 2000·Infectious Disease Clinics of North America·E C JohannsenL C Madoff
Jun 27, 2001·American Journal of Surgery·J A Alvarez PérezJ I Jorge
Jan 22, 2002·Bulletin Du Groupèment International Pour La Recherche Scientifique En Stomatologie & Odontologie·J R Fricton
Aug 9, 2002·Journal of Gastroenterology and Hepatology·Wai-Man WongChing Lung Lai
Nov 20, 2002·Archives of Internal Medicine·Ebbing LautenbachBrian L Strom
Oct 3, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph S SolomkinInfectious Diseases Society of America
Jun 9, 2004·Journal of Clinical Microbiology·Hsin-Ling LeeKuan-Wen Chen
Jan 1, 1950·Cancer·W J YOUDEN
Dec 4, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph RahimianRobert S Holzman
May 17, 2006·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C-B HsiehJ-C Yu
Aug 29, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Yu-Lin LeeYung-Ching Liu
Mar 3, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Sang-Won ParkEu-Suk Kim
Aug 19, 2007·The American Journal of the Medical Sciences·Shiuan-Chih ChenWilliam R Bell
Sep 18, 2007·European Journal of Gastroenterology & Hepatology·José Juan Ruiz-HernándezPedro Betancor-León

Citations

Aug 10, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shiuan-Chih ChenMeng-Chih Lee
Oct 2, 2013·The Indian Journal of Surgery·Dhaval O MangukiyaSaurabh T Gupta
Apr 27, 2012·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Barbara AlkoferLaurence Chiche
Mar 26, 2011·BMC Research Notes·Helen M HeneghanRonan Waldron
May 27, 2010·World Journal of Gastroenterology : WJG·Herwig Cerwenka
Nov 15, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Young-Gi MinChi Keung Chan
Apr 30, 2013·The American Journal of Emergency Medicine·Sheng-Hung KuoMeng-Chih Lee
Aug 28, 2013·Asian Journal of Surgery·Harry Hok Tee YuTan To Cheung
Jun 3, 2015·American Journal of Surgery·Saleem AhmedVishal G Shelat
Oct 24, 2014·Journal of Hepato-biliary-pancreatic Sciences·Joseph Zhi Wen LoWinston Wei Liang Woon
Nov 16, 2013·Scandinavian Journal of Infectious Diseases·Jai Hoon YoonDong Joon Kim
Oct 20, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Mrudula PatelAhmed A Wadee
Oct 6, 2016·Anaerobe·Nurver Ulger ToprakGuner Soyletir
Jun 29, 2017·Clinical and Molecular Hepatology·Seon-Jae KimHyeok Choon Kwon
Oct 24, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Kang Hoon LeeYong Wonn Kwon
May 22, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·A Reum ChoYoung Woo Kang
Feb 27, 2018·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Kwang Soon ParkKeon Kim
Sep 28, 2017·Open Forum Infectious Diseases·Megan C Gallagher, Mary-Margaret Andrews
Mar 15, 2018·Annals of Hepato-biliary-pancreatic Surgery·Coeway Boulder ThngVishal G Shelat
Mar 3, 2021·Journal of Pediatric Nursing·Yu-Jung ChangShiuan-Chih Chen

Related Concepts

Antibiotics
Alkalescens-Dispar Group
Escherichia Coli Infections
Klebsiella Infections
Klebsiella rhinoscleromatis
Receiver Operating Characteristic
Severity of Illness Index
Multivariate Analysis
Apache III
Liver Abscess, Pyogenic

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