Severity of hypoglycaemia and health-related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe

Endocrinology, Diabetes & Metabolism
Manjiri PawaskarKristy Iglay

Abstract

Hypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health-related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients with T2DM. European patients with T2DM selected from the National Health and Wellness Survey who were currently receiving pharmacologic therapy were stratified into 3 groups based on the reported history and severity of hypoglycaemic events (no event, nonsevere, severe) experienced in the previous 3 months. Patients' work productivity, HRQoL, healthcare resource use (HCRU) and associated costs were assessed as self-reported outcomes. Of 1269 patients included in the study, 652 (51.4%) patients had not experienced an event, while 533 (42.0%) and 84 (6.6%) patients had experienced nonsevere and severe hypoglycaemic events, respectively, in the previous 3 months. An increase in hypoglycaemia severity was associated with a decrease in HRQoL, and an increase in HCRU and healthcare costs. The impact of hypoglycaemia varies by severity and has a negative impact on HRQoL and overall HCRU and costs.

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Citations

Sep 11, 2019·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Alexandria Ratzki-LeewingStewart B Harris
Apr 8, 2020·International Journal of Endocrinology·Gebrewahd Bezabh Gebremichael, Teklewoini Mariye Zemicheal
Jul 22, 2021·Journal of Comparative Effectiveness Research·Xuanqian XieAndrei Volodin

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