Severity of primary open-angle glaucoma in patients with hypertension and diabetes

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
Anadi KhatriMuna Kharel

Abstract

Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with numerous risk factors. Its severity with associated risk factors remains a widely debated topic. To evaluate the severity of POAG in patients with hypertension (HTN) and diabetes or both. This hospital-based, cross-sectional descriptive study was conducted for a period of 18 months from January 2016 to June 2017. Diagnosed cases of POAG were evaluated for severity with associated risk factors. A total of 221 patients were enrolled in the study. The mean age of the patients was 54.4 (SD ± 15.9) years with a male to female ratio of 0.93:1. Of the 221 patients, 68 (31%) had a family history of POAG. Mean intraocular pressure was 15.8±4.87 mmHg, and mean central corneal thickness was 535.4±34.9 μm. A total of 81 (36%) patients had HTN, 21 (9.50%) had diabetes mellitus (DM), and 15 (6.80%) had both HTN and DM. Analysis using SPSS version 20 was done. The severity of POAG was found to be significantly higher in patients with HTN, DM, or both when evaluated on the basis of anatomical and functional loss. POAG patients with HTN, DM, or both were found to have more severe POAG. Patients with these risk factors could represent "high-risk patients" with POAG. Patien...Continue Reading

Citations

Mar 15, 2020·Journal of Clinical Medicine·Andrzej GrzybowskiCarlos Gustavo De Moraes
Apr 13, 2021·European Journal of Ophthalmology·Mansi BatraMohamed Aly Morsy
Sep 9, 2021·Current Diabetes Reports·Yangjiani LiNazlee Zebardast

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