Severity of vision loss interacts with word-specific features to impact out-loud reading in glaucoma

Investigative Ophthalmology & Visual Science
Priya M MathewsPradeep Y Ramulu

Abstract

To assess the impact of glaucoma-related vision loss on measures of out-loud reading, including time to say individual words, interval time between consecutive words, lexical errors, skipped words, and repetitions. Glaucoma subjects (n = 63) with bilateral visual field loss and glaucoma suspect controls (n = 57) were recorded while reading a standardized passage out loud. A masked evaluator determined the start and end of each recorded word and identified reading errors. Glaucoma subjects demonstrated longer durations to recite individual words (265 vs. 243 ms, P < 0.001), longer intervals between words (154 vs. 124 ms, P < 0.001), and longer word/post-word interval complexes (the time spanned by the word and the interval following the word; 419 vs. 367 ms, P < 0.001) than controls. In multivariable analyses, each 0.1 decrement in log contrast sensitivity (logCS) was associated with a 15.0 ms longer word/post-interval complex (95% confidence interval [CI] = 9.6-20.4; P < 0.001). Contrast sensitivity was found to significantly interact with word length, word frequency, and word location at the end of a line with regards to word/post-word interval complex duration (P < 0.05 for all). Glaucoma severity was also associated with mor...Continue Reading

Citations

Mar 8, 2016·American Journal of Ophthalmology·Anjali M BhoradeDavid Carr
Aug 31, 2018·Journal of Glaucoma·Ayodeji E Sotimehin, Pradeep Y Ramulu
Dec 21, 2018·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Teresa RolleRaffaele Nuzzi
Jul 28, 2016·The British Journal of Ophthalmology·Priya M MathewsEsen K Akpek

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