PMID: 10774610Apr 25, 2000Paper

Sevoflurane and anesthesia for neurosurgery: a review

Journal of Neurosurgical Anesthesiology
C M Duffy, B F Matta


This review assesses the extent to which sevoflurane fulfills the requirements of the ideal inhalational agent for use in neuroanesthetic practice. Sevoflurane's pharmacokinetic profile is outlined. Data from animal and human studies are used to discuss its effects on cerebral hemodynamics, central nervous system monitoring, and cardiovascular parameters. Where possible, sevoflurane is compared with isoflurane, currently considered the inhalational agent of choice in neuroanesthesia. Sevoflurane's potential for toxicity is reviewed.


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May 7, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Hugo E CastagniniMichael H Nathanson
Aug 13, 2002·Journal of Neurosurgical Anesthesiology·Morten C MoeMorten L Vinje
Mar 27, 2003·Journal of Neurosurgical Anesthesiology·Kiyoshi NagaseShuji Dohi
Jun 27, 2003·Journal of Neurosurgical Anesthesiology·Morten C MoeMorten L Vinje
Jun 23, 2009·Journal of Neurosurgical Anesthesiology·Deepak SinghParmod K Bithal
Apr 23, 2004·Acta Anaesthesiologica Scandinavica·M C MoeJ Berg-Johnsen
Jan 7, 2004·Anaesthesia·Nick Hirsch
Mar 18, 2004·Acta Anaesthesiologica Scandinavica·A HolmströmJ Akeson
Nov 27, 2008·Acta Anaesthesiologica Scandinavica·Ravi BainsJ Berg-Johnsen
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Dec 17, 2009·Acta Anaesthesiologica Scandinavica·L SchlünzenG E Cold
Mar 19, 2014·Journal of Neurosurgical Anesthesiology·Ayman A GhoneimMohammed A El Beltagy
Mar 24, 2016·BMC Anesthesiology·Jasmina Markovic-BozicVesna Novak-Jankovic
Jan 8, 2021·Journal of Biomolecular Structure & Dynamics·Jamelah S Al-OtaibiY Shyma Mary
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