Sevoflurane versus propofol for interventional neuroradiology: a comparison of the maintenance and recovery profiles at comparable depths of anesthesia

Korean journal of anesthesiology
Eun-Su ChoiYoung-Tae Jeon


Sevoflurane and propofol are used widely for interventional neuroradiology (INR). Using the bispectral index (BIS), we compared the clinical properties of sevoflurane and propofol anesthesia in patients undergoing INR at comparable depths of anesthesia. The patients were allocated randomly into two groups. The sevoflurane group received propofol (1.5 mg/kg), alfentanil (5 µg/kg), and rocuronium (0.6 mg/kg) for induction, and the propofol group was induced with a target effect-site concentration of propofol (4 µg/ml), alfentanil (5 µg/kg), and rocuronium (0.6 mg/kg). After intubation, anesthesia was maintained with sevoflurane or propofol with 67% nitrous oxide in 33% oxygen. Sevoflurane and propofol concentrations were titrated to maintain the BIS at 50-60. Phenylephrine or opioid was used to maintain the mean arterial pressure within 20% of the baseline values. The amounts of phenylephrine or alfentanil used, the number of patients showing movement during the procedure, and the recovery times were recorded. Compared to the propofol group, the sevoflurane group showed faster recovery in spontaneous ventilation, eye opening, extubation, and orientation (4 vs. 7 min, 7 vs. 9 min, 8 vs. 10 min, 10 vs. 14 min, respectively; P < 0.0...Continue Reading


Jul 1, 1990·Anesthesiology·C C Hug
Nov 1, 1965·Anesthesiology·E I EgerB Brandstater
Feb 1, 1994·Anesthesia and Analgesia·T J Ebert, M Muzi
Feb 18, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·W D MiA Matsuki
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May 7, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Hugo E CastagniniMichael H Nathanson
Jun 15, 2007·British Journal of Anaesthesia·M K VarmaG Kessell

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