Sex and Gender Differences in Prevention of Type 2 Diabetes

Frontiers in Endocrinology
Jürgen Harreiter, Alexandra Kautzky-Willer

Abstract

Lifestyle intervention programs are effective in the prevention of type 2 diabetes mellitus (T2DM) in high risk populations. However, most studies only give limited information about the influence of sex and/or gender effectiveness of these interventions. So far, similar outcome was reported for diabetes progression and weight loss. Nevertheless, long-term data on cardiovascular outcome are sparse but favoring women regarding all-cause and cardiovascular mortality. In both men and women, sex hormone imbalances and reproductive disorders are associated with a higher risk of T2DM development. Diabetes prevention approaches are reported for polycystic ovary syndrome, gestational diabetes mellitus, and erectile dysfunction and are presented in this review. In the surgical treatment options for morbid obese patients, sex and gender differences are present. Choices and preferences of adherence to lifestyle and pharmacological interventions, expectations, treatment effects, and complications are influenced by sex or gender. In general, bariatric surgery is performed more often in women seeking medical/surgical help to lose weight. Men are older and have higher comorbidities and mortality rates and worse follow-up outcome after bariatr...Continue Reading

References

Apr 1, 2004·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Jane WardleFrance Bellisle
Apr 10, 2004·Obesity Surgery·Marije LibetonPaul E O'Brien
May 20, 2005·International Journal of Impotence Research·K Esposito, D Giugliano
Mar 16, 2006·JAMA : the Journal of the American Medical Association·Eric L DingSimin Liu
Nov 22, 2008·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J C LovejoyUNKNOWN Stock Conference 2008 Working Group
Jun 6, 2009·European Journal of Clinical Investigation·A Kautzky-Willer, A Handisurya
Oct 5, 2010·Fertility and Sterility·Lourdes IbáñezFrancis de Zegher
Oct 26, 2010·International Journal of Behavioral Medicine·William L Dunlop, Mark R Beauchamp
Nov 3, 2010·The Journal of Sexual Medicine·Francesco MontorsiMarlene Wasserman
Apr 7, 2011·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Julie A QuinlivanJane Fisher
Apr 30, 2011·Obesity·Laura P SvetkeyUNKNOWN Weight Loss Maintenance Collaborative Research Group
May 11, 2011·The Journal of Sexual Medicine·Manuel de J Araña RosaínzRamiro Fragas Valdés
Jun 3, 2011·The Journal of Clinical Endocrinology and Metabolism·Lourdes IbáñezFrancis de Zegher
Jan 24, 2012·British Journal of Sports Medicine·Nicola W BurtonWendy J Brown
Jul 17, 2012·Advances in Nutrition·Rebecca Kanter, Benjamin Caballero
Jul 24, 2012·Lancet·Harold W KohlUNKNOWN Lancet Physical Activity Series Working Group
Apr 25, 2013·Obesity Surgery·Christine StrohUNKNOWN Obesity Surgery Working Group, Competence Network Obesity
May 3, 2013·Diabetes Care·Kathryn BackholerDianna J Magliano
Sep 10, 2013·The Journal of Sexual Medicine·Aviva E WeinbergJohn T Leppert
Oct 26, 2013·Diabetes Care·Cathy E ElksUNKNOWN InterAct Consortium
Dec 18, 2013·Women's Health·Jürgen HarreiterAlexandra Kautzky-Willer
Feb 12, 2014·BMJ : British Medical Journal·Jodie M DoddUNKNOWN LIMIT Randomised Trial Group
Feb 22, 2014·Asian Journal of Andrology·Xiang CaiKun-Jie Wang
Mar 29, 2014·Acta Diabetologica·Mohsen JanghorbaniElham Hosseini
Jun 20, 2014·Scandinavian Journal of Medicine & Science in Sports·M MohrP Krustrup
Jun 20, 2014·Scandinavian Journal of Medicine & Science in Sports·M V de SousaM E R da Silva
Jul 16, 2014·Nature Reviews. Endocrinology·Channa N Jayasena, Stephen Franks
Oct 8, 2014·American Journal of Health Behavior·NiCole R KeithDaniel O Clark
Nov 29, 2014·Obesity Surgery·Zhamak KhorgamiNestor de la Cruz-Muñoz
Dec 4, 2014·Diabetologia·Anna GlechnerAlexandra Kautzky-Willer

❮ Previous
Next ❯

Citations

Nov 1, 2018·Nature Reviews. Endocrinology·Alexandra Kautzky-Willer, Jürgen Harreiter
Jan 5, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Almudena Carneiro-BarreraGualberto Buela-Casal
Apr 14, 2019·Wiener klinische Wochenschrift·Jürgen Harreiter, Michael Roden
Apr 14, 2019·Wiener klinische Wochenschrift·Alexandra Kautzky-WillerMonika Lechleitner
Apr 14, 2019·Wiener klinische Wochenschrift·Alexandra Kautzky-WillerRaimund Weitgasser
Aug 24, 2018·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Feng-Fei LiJian-Hua Ma
Dec 20, 2018·Frontiers in Endocrinology·Cathleen JohnTilman Grune
Aug 17, 2020·International Journal of Environmental Research and Public Health·Hyun Sook Oh
Oct 10, 2020·Current Diabetes Reports·Jürgen HarreiterDavid Simmons
Feb 4, 2021·Animal Models and Experimental Medicine·Christopher M LawsonCraig F Ferris
Nov 5, 2020·Journal of Clinical Medicine·Diana OliveiraPatrícia Lourenço
Jan 16, 2021·American Journal of Physiology. Heart and Circulatory Physiology·M Dennis LeoJonathan H Jaggar
Mar 4, 2021·Pharmacological Reviews·Franck Mauvais-JarvisJoshua B Rubin
May 27, 2020·Journal of Proteome Research·Xi ZhangHongchang Gao

❮ Previous
Next ❯

Methods Mentioned

BETA
gastric bypass
testosterone replacement therapy
SGA
hormone replacement therapy

Software Mentioned

HATTRICK

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Diabetes Research and Clinical Practice
Alexandra Kautzky-Willer, Jürgen Harreiter
Duodecim; lääketieteellinen aikakauskirja
Tiina Koskela-KoivistoAila Tiitinen
© 2022 Meta ULC. All rights reserved