Sex and Race Differences in Pain Sensitization among Patients with Chronic Low Back Pain

The Journal of Pain : Official Journal of the American Pain Society
Samantha M MeintsRobert R Edwards

Abstract

Growing evidence suggests that chronic low back pain (CLBP) is associated with pain sensitization, and that there are sex and race disparities in CLBP. Given the sex and race differences in pain sensitization, this has been hypothesized as a mechanism contributing to the sex and race disparities in CLBP. This study examined sex and race differences in pain sensitization among patients with CLBP, as well as the role of catastrophizing as a potential mediator of those differences. The study found that compared with men, women required less pressure to produce deep muscle pain and rated mechanical punctate pain as more painful. Compared with non-Hispanic white patients, black patients demonstrated greater pain sensitivity for measures of deep muscle hyperalgesia and mechanical punctate pain. Furthermore, catastrophizing partially mediated the race differences in deep muscle pain such that black participants endorsed greater pain catastrophizing, which partially accounted for their increased sensitivity to, and temporal summation of, deep muscle pain. Taken together, these results support the need to further examine the role of catastrophizing and pain sensitization in the context of sex and race disparities in the experience of CL...Continue Reading

Citations

Dec 17, 2019·Alcoholism, Clinical and Experimental Research·Scott EdwardsKatie Witkiewitz
Feb 26, 2020·European Journal of Pain : EJP·Christine H Meyer-FrießemJan Vollert
Aug 4, 2019·Journal of Behavioral Medicine·R Kathryn McHughRoger D Weiss
Jan 13, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Teddy G GoetzCarolyn M Mazure
Dec 29, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Mary E Morales, R Jason Yong
May 11, 2021·International Journal of Occupational Safety and Ergonomics : JOSE·Sirinant ChannakPrawit Janwantanakul
May 26, 2021·The Journal of Pain : Official Journal of the American Pain Society·Dottington FullwoodEllen L Terry
Sep 23, 2021·Pain Practice : the Official Journal of World Institute of Pain·Manisha Subramanian, Prem Venkatesan
Jan 15, 2021·American Journal of Physical Medicine & Rehabilitation·Linda ResnikMelissa A Clark
Feb 3, 2022·Pain and Therapy·Larissa J Strath, Robert E Sorge
Feb 8, 2022·Journal of Osteopathic Medicine·Sondos Al Sad, Amanda R Start

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.