Abstract
Analysis of general surgery literature has revealed noteworthy sex bias and underreporting. Our objective was to determine the prevalence of sex bias and underreporting in rhinology. All articles in 2016 issues of Rhinology, the American Journal of Rhinology and Allergy (AJRA), and the International Forum of Allergy and Rhinology (IFAR) were reviewed. Of 369 articles, 248 met inclusion criteria. Excluded studies were cadaveric, meta-analysis/review, and editorial. Data collected included study type, demographics, and sex-based statistical analysis. There were 202 clinical and 46 basic science/translational studies. From 188 of 202 clinical studies with known sex, 1 included participants of a single sex. Sex matching >50% (SM50 ) was found in 81.9%, and 55.9% performed sex-based statistical analysis. Domestic clinical studies performed sex-based analysis more frequently than international (54.9% vs 44.4%) and exhibited a higher rate of SM50 (84.5% vs 80.3%), though these differences were not statistically significant. For basic/translational studies, 54.5% (24/44) provided sex breakdown. Among these, 29.2% included 1 sex, and 8.3% performed sex-based analysis. Of 10 using animals, 70.0% utilized 1 sex. The remaining 30.0% did no...Continue Reading
References
Jul 11, 2001·Journal of Women's Health & Gender-based Medicine
Jun 7, 2002·Archives of Otolaryngology--head & Neck Surgery·Andreas F P TemmelThomas Hummel
Nov 13, 2002·JAMA : the Journal of the American Medical Association·Claire MurphyDavid M Nondahl
Nov 30, 2006·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Flavia FranconiVincenzo Cuomo
Oct 30, 2007·Pain·Joel D GreenspanUNKNOWN Consensus Working Group of the Sex, Gender, and Pain SIG of the IASP
May 23, 2009·Inhalation Toxicology·Guilherme J M GarciaJulia S Kimbell
Feb 2, 2010·Trends in Pharmacological Sciences·Tamara J NicolsonRuth R A Roberts
Jul 14, 2010·Neuroscience and Biobehavioral Reviews·Annaliese K Beery, Irving Zucker
Mar 1, 2011·Journal of Women's Health·Stacie E GellerMolly Carnes
Oct 13, 2012·Nature·Story C LandisShai D Silberberg
Aug 9, 2013·The New England Journal of Medicine·Ronald H FarkasRobert Temple
Jan 25, 2014·Neuroscience and Biobehavioral Reviews·Brian J PrendergastIrving Zucker
Feb 1, 2014·Nature·Francis S Collins, Lawrence A Tabak
Sep 2, 2014·Surgery·Dustin Y YoonMelina R Kibbe
Feb 1, 2015·International Journal for Equity in Health·Jacqueline GahaganArdath Whynacht
Jul 23, 2015·Clinical Orthopaedics and Related Research·Carolyn M HettrichJo A Hannafin
Oct 28, 2015·BMC Women's Health·Carolyn M Mazure, Daniel P Jones
Jul 29, 2016·Biology of Sex Differences·Jill B BeckerJing W Liang
Aug 24, 2016·JAMA Surgery·Neel A MansukhaniMelina R Kibbe
Sep 28, 2016·Hypertension·Alex DaytonAllen W Cowley
Sep 25, 2017·Noise & Health·Amanda Marie Lauer, Katrina Marie Schrode
Dec 6, 2017·World Journal of Otorhinolaryngology - Head and Neck Surgery·Julia NoelZara M Patel