Sex-biased lethality or transmission of defective transcription machinery in Arabidopsis.

Genetics
Yasuyuki OnoderaCraig S Pikaard

Abstract

Unlike animals, whose gametes are direct products of meiosis, plant meiotic products undergo additional rounds of mitosis, developing into multicellular haploid gametophytes that produce egg or sperm cells. The complex development of gametophytes requires extensive expression of the genome, with DNA-dependent RNA polymerases I, II, and III being the key enzymes for nuclear gene expression. We show that loss-of-function mutations in genes encoding key subunits of RNA polymerases I, II, or III are not transmitted maternally due to the failure of female megaspores to complete the three rounds of mitosis required for the development of mature gametophytes. However, male microspores bearing defective polymerase alleles develop into mature gametophytes (pollen) that germinate, grow pollen tubes, fertilize wild-type female gametophytes, and transmit the mutant genes to the next generation at moderate frequency. These results indicate that female gametophytes are autonomous with regard to gene expression, relying on transcription machinery encoded by their haploid nuclei. By contrast, male gametophytes make extensive use of transcription machinery that is synthesized by the diploid parent plant (sporophyte) and persists in mature polle...Continue Reading

References

Feb 1, 1984·Molecular and Cellular Biology·R Miesfeld, N Arnheim
Mar 11, 1982·Nature·I GrummtM R Paule
Feb 25, 1993·Nucleic Acids Research·R Larkin, T Guilfoyle
May 26, 1998·Seminars in Cell & Developmental Biology·U Grossniklaus, K Schneitz
Feb 24, 2000·Nucleic Acids Research·M R Paule, R J White
Dec 29, 2000·Nature·UNKNOWN Arabidopsis Genome Initiative
Aug 25, 2001·Science·T HigashiyamaT Kuroiwa
Mar 7, 2002·Developmental Cell·Mark A Johnson, Daphne Preuss
Oct 1, 1993·The Plant Cell·S. McCormick
Oct 1, 1993·The Plant Cell·J. P. Mascarenhas
Jul 1, 1989·The Plant Cell·J. P. Mascarenhas
Nov 14, 2002·Annual Review of Genetics·Gary N Drews, Ramin Yadegari
Dec 24, 2002·Current Opinion in Plant Biology·Tetsuya HigashiyamaTsuneyoshi Kuroiwa
Jan 10, 2003·Nucleic Acids Research·Iris TzafrirDavid Meinke
Jun 14, 2003·Plant Physiology·David Honys, David Twell
Jul 29, 2003·Journal of Plant Research·Tetsuya Higashiyama
Aug 2, 2003·Science·José M AlonsoJoseph R Ecker
Mar 24, 2004·The Plant Cell·Sheila McCormick
Jul 22, 2004·Plant Physiology·Iris TzafrirDavid Meinke
Nov 13, 2004·Genome Biology·David Honys, David Twell
Feb 11, 2005·The Plant Journal : for Cell and Molecular Biology·Stefanie SprunckThomas Dresselhaus
Jan 31, 2006·The Plant Journal : for Cell and Molecular Biology·Keith W EarleyCraig S Pikaard
Feb 3, 2007·The Plant Journal : for Cell and Molecular Biology·Shin-nosuke HashidaHirofumi Uchimiya
Jun 15, 2007·The Plant Journal : for Cell and Molecular Biology·Joshua G SteffenGary N Drews
Sep 8, 2007·Plant Physiology·Aleel K Grennan

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Citations

May 21, 2013·Molecular Biology and Evolution·Péter SzövényiAndreas Wagner
Dec 14, 2011·PloS One·Rosanna MurallaDavid Meinke
Dec 17, 2015·Proceedings of the National Academy of Sciences of the United States of America·Sarah P OttoSimone Immler
May 29, 2012·The Plant Journal : for Cell and Molecular Biology·Pururawa MayankUeli Grossniklaus
Nov 12, 2014·The Plant Journal : for Cell and Molecular Biology·Ryuji TsugekiKiyotaka Okada
May 7, 2015·The Plant Journal : for Cell and Molecular Biology·Hirotomo TakatsukaMasaaki Umeda
Oct 26, 2014·Proceedings of the National Academy of Sciences of the United States of America·Zsuzsanna MéraiHisashi Tamaru
May 3, 2012·Cell Reports·Ek Han TanCraig S Pikaard
Nov 6, 2018·Nature Communications·Peter KindgrenSebastian Marquardt
Feb 28, 2020·EMBO Reports·Xueyuan LengSebastian Marquardt
May 28, 2019·Frontiers in Plant Science·Hyo-Young ParkJeong-Kook Kim
Jun 9, 2017·G3 : Genes - Genomes - Genetics·Giao Ngoc NguyenAtsushi Yoshimura
Nov 16, 2021·The Plant Journal : for Cell and Molecular Biology·Takamasa SuzukiKenzo Nakamura

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