Sex-chromosome turnovers: the hot-potato model

The American Naturalist
Olivier BlaserNicolas Perrin

Abstract

Sex-determining systems often undergo high rates of turnover but for reasons that remain largely obscure. Two recent evolutionary models assign key roles, respectively, to sex-antagonistic (SA) mutations occurring on autosomes and to deleterious mutations accumulating on sex chromosomes. These two models capture essential but distinct key features of sex-chromosome evolution; accordingly, they make different predictions and present distinct limitations. Here we show that a combination of features from the two models has the potential to generate endless cycles of sex-chromosome transitions: SA alleles accruing on a chromosome after it has been co-opted for sex induce an arrest of recombination; the ensuing accumulation of deleterious mutations will soon make a new transition ineluctable. The dynamics generated by these interactions share several important features with empirical data, namely, (i) that patterns of heterogamety tend to be conserved during transitions and (ii) that autosomes are not recruited randomly, with some chromosome pairs more likely than others to be co-opted for sex.

References

Feb 1, 1996·Current Biology : CB·B Charlesworth
Feb 5, 2003·Genome Research·Rachael A WoramRoy G Danzmann
Oct 19, 2007·Nature·G S van Doorn, M Kirkpatrick
Apr 9, 2008·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·J-N VolffM Schartl
Apr 9, 2008·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·I Miura
Aug 18, 2009·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·J E Mank, J C Avise
Mar 6, 2010·Aquatic Toxicology·Allen W OlmsteadSigmund J Degitz
May 6, 2010·Genome Biology·Jennifer A Marshall Graves, Catherine L Peichel
Jul 16, 2010·Genetics·G Sander van Doorn, Mark Kirkpatrick
Jun 2, 2011·PLoS Biology·Matthias StöckNicolas Perrin
Jan 6, 2012·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Denis O'MeallyJennifer A Marshall Graves
Aug 21, 2012·Journal of Evolutionary Biology·R F GuerreroN Perrin
Jul 31, 2013·Evolution; International Journal of Organic Evolution·Alan BrelsfordNicolas Perrin

❮ Previous
Next ❯

Citations

Dec 22, 2015·Fungal Biology Reviews·Alexander IdnurmTatiana Giraud
Sep 12, 2014·Evolution; International Journal of Organic Evolution·Christophe DufresnesNicolas Perrin
Aug 19, 2015·Proceedings of the National Academy of Sciences of the United States of America·Manfred Schartl
May 10, 2015·Molecular Biology and Evolution·Christophe DufresnesNicolas Perrin
Feb 28, 2016·Evolution; International Journal of Organic Evolution·Alan BrelsfordNicolas Perrin
Feb 17, 2018·Molecular Ecology·Matthew W PennellCatherine L Peichel
Aug 28, 2018·PLoS Biology·Jacob A TennessenTia-Lynn Ashman
May 8, 2019·Molecular Ecology·Michail RovatsosLukáš Kratochvíl
Sep 21, 2019·Molecular Ecology·Daniela H PalmerAlison E Wright
Nov 24, 2019·Journal of Evolutionary Biology·Paris VeltsosNicolas Perrin
Apr 22, 2020·Genome Biology and Evolution·Benjamin L S FurmanJudith E Mank
Jul 11, 2020·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Richard P Meisel
Apr 26, 2017·Scientific Reports·Thomas BeckingClément Gilbert
Nov 27, 2019·Nature Ecology & Evolution·Beatriz Vicoso
Nov 12, 2019·Molecular Biology and Evolution·Caroline M S CauretBen J Evans
Apr 10, 2017·Genome Biology and Evolution·Aline MuyleGabriel Ab Marais
Oct 7, 2018·Nature Communications·Daniel L JeffriesNicolas Perrin
Feb 2, 2019·Scientific Reports·Veronika BalounovaBohuslav Janousek
Oct 6, 2020·Evolution Letters·Christophe DufresnesDaniel L Jeffries
Dec 29, 2017·Journal of Evolutionary Biology·E CavotoN Perrin
Nov 27, 2019·Nature Ecology & Evolution·Devon E PearseSigbjørn Lien
May 5, 2017·Proceedings. Biological Sciences·Jessica K AbbottBengt Hansson
Nov 5, 2020·Cells·Worapong SingchatKornsorn Srikulnath
Aug 8, 2020·Molecular Biology and Evolution·Christophe DufresnesNicolas Perrin
Dec 8, 2020·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Wenjing TaoThomas D Kocher
Feb 2, 2021·Frontiers in Plant Science·Ana Paula Leite MontalvãoNiels Andreas Müller
Feb 10, 2021·G3 : Genes - Genomes - Genetics·Takahiro Sakamoto, Hideki Innan
Feb 17, 2021·Evolution; International Journal of Organic Evolution·Deborah Charlesworth
Apr 4, 2021·Genes·Wen-Juan Ma, Paris Veltsos
Jul 13, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Nicolas Perrin
Jul 13, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Daniel L JeffriesJohn R Pannell
Aug 10, 2021·PLoS Genetics·Deborah CharlesworthKaren Keegan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Evolution; International Journal of Organic Evolution
Christine GrossenNicolas Perrin
Evolution; International Journal of Organic Evolution
Alan BrelsfordNicolas Perrin
Evolution; International Journal of Organic Evolution
Brian CharlesworthDeborah Charlesworth
© 2021 Meta ULC. All rights reserved