Sex determination in hydra: control by a subpopulation of interstitial cells in Hydra oligactis males

Developmental Biology
C L Littlefield

Abstract

The stability of sexual phenotype was examined in a single clone of Hydra oligactis males maintained at two culture temperatures, 18 and 22 degrees C. At these temperatures animals of this species do not reproduce sexually, but reproduce asexually by budding, and males and females are morphologically indistinguishable. When the temperature is lowered to 10 degrees C gametogenesis is induced and sexual phenotype can be assayed. Males cultured for several years at 18 degrees C expressed a stable sexual phenotype when induced to undergo gametogenesis; males remained male. Those cultured at 22 degrees C for 1 year, however, expressed a low frequency of sex reversal from male to female; males ceased sperm differentiation and began producing eggs. Male sex reversal in cultures maintained at the higher temperature was correlated with the loss of a specific subpopulation of interstitial cells, those that bind the monoclonal antibody, AC2, which labels cells specific to the spermatogenic pathway in H. oligactis males. When interstitial cells restricted to this pathway were reintroduced into sex-reversed males (phenotypic females), the male phenotype was reestablished and animals reverted to sperm production. To further investigate the r...Continue Reading

Citations

Mar 1, 1992·Developmental Biology·T Fujisawa
Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·T C Bosch, C N David
Sep 19, 2009·Seminars in Cell & Developmental Biology·Hiroshi WatanabeThomas W Holstein
Mar 25, 2014·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Johanna FrauneRicardo Benavente
Aug 18, 2016·Molecular Reproduction and Development·Stefan Siebert, Celina E Juliano
Nov 1, 1991·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Thomas C G BoschCharles N David
Jan 20, 2021·Molecular Ecology·Máté MiklósJácint Tökölyi

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