PMID: 18406823Apr 15, 2008Paper

Sex-determining genes

Trends in Endocrinology and Metabolism : TEM
K McElreavey, M Fellous

Abstract

Recently, a number of genes have been identified that are associated with a failure of human sex determination, including WT1, DAX-1, SOX9, ATRX, and the Y-linked testis determination gene, SRY. Most cases of human sex reversal, XY females and XX males, do not, however, appear to be caused by mutations in these genes. This review highlights recent advances in this field and discusses the prospects of identifying genes in the sex-determining pathway.

References

May 1, 1994·American Journal of Medical Genetics·J M OpitzV L Smith
Jan 13, 1994·The New England Journal of Medicine·G S TintG Salen
Jun 1, 1993·Journal of Medical Genetics·C P BennettD Grant
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·K McElreaveyM Fellous
Mar 1, 1996·Medicine·R J Gibbons, D R Higgs
Jun 1, 1996·Journal of Medical Genetics·C KwokJ R Hawkins
Mar 1, 1996·Current Biology : CB·M J BitgoodA P McMahon
Jan 1, 1997·Clinical Dysmorphology·M J SellerM Newbould
Aug 1, 1996·Trends in Endocrinology and Metabolism : TEM·K L Parker, B P Schimmer

❮ Previous
Next ❯

Citations

Sep 14, 2001·The Journal of Experimental Zoology·M BullejosP Koopman
Sep 17, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F BretelleY Ville
Apr 10, 2007·Trends in Ecology & Evolution·Tobias UllerJan Komdeur
Jul 3, 2002·Journal of Pediatric Endocrinology & Metabolism : JPEM·Michael P Wajnrajch
Dec 16, 2018·Scientific Reports·Melissa C KeinathJeramiah J Smith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
N LazebnikW A Hogge
© 2022 Meta ULC. All rights reserved