Sex difference in heritability of BMI in South Korean adolescent twins

Obesity
Yoon-Mi Hur

Abstract

Twin studies of BMI on the basis of Asian twins are extremely rare. Eight hundred eighty-eight pairs of twins [279 monozygotic (MZ) and 82 dizygotic (DZ) pairs of male twins, 319 MZ and 82 DZ pairs of female twins, and 126 opposite-sex pairs of DZ twins] completed items concerning height and weight through a mail and a telephone survey. A general sex-limitation model was applied to the data. Heritability estimate was greater among women than among men. However, there was little evidence of sex-specific genes. Under the best-fitting model, additive genetic variances were 82% [95% confidence interval (CI): 72% to 95%] for men and 87% (95% CI: 77% to 99%) for women; shared environmental variances were negligible in both men and women. These estimates of genetic and environmental factors in BMI found among South Korean adolescent twins were broadly in the range of those reported in previous studies of BMI based on Western twin samples.

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Citations

Jan 21, 2010·Behavior Genetics·Brett C HaberstickJohn K Hewitt
Dec 1, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi HurTae-Bok Song
Sep 10, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y-M HurK Mitchell
Sep 16, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K SilventoinenT I A Sørensen
Apr 2, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·H-R LajunenK Silventoinen
Mar 1, 2014·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Fuling JiKarri Silventoinen
Aug 29, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J MinY Wang
Jul 30, 2014·Medicina clínica·Carmen Iranzo-TatayLuis Rojo-Moreno
Apr 14, 2015·Preventive Nutrition and Food Science·Miae Doo, Yangha Kim
Oct 8, 2008·Diabetologia·M C ZillikensC M van Duijn
Mar 20, 2012·European Journal of Epidemiology·Cassandra NanMaurice Zeegers
Dec 27, 2019·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi HurJong Woo Kim
Aug 11, 2020·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Yoon-Mi Hur
Dec 8, 2017·Diabetes·Mingyang SongEdward L Giovannucci

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