Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British regional heart study

Journal of Epidemiology and Community Health
Debbie A LawlorGeorge Davey Smith

Abstract

To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT). Cross sectional survey. Two British towns. 800 men and women aged 56-75 years. Carotid IMT. There was a continuous linear association between waist-hip ratio and IMT in both men and women. The magnitude of the association between waist to hip ratio and IMT was identical in both sexes. In age adjusted analyses IMT was 14% greater in men compared with women (age adjusted male to female ratio of geometric means 1.14; 95% confidence interval 1.07 to 1.21) with adjustment for waist to hip ratio this attenuated to no difference (1.00; 0.92 to 1.09). Adjustment for body mass index and for lifestyle risk factors had very little effect on the sex difference in mean intima media thickness. Sex differences in body fat distribution may explain sex differences in arterial atherosclerosis.

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Citations

Oct 3, 2007·Internal and Emergency Medicine·R TarquiniG F Gensini
Aug 5, 2010·Clinical Medicine & Research·Lauren C SchrampJulie Hoff
Feb 27, 2007·Genetic Epidemiology·Lin PanMark Abney
Dec 23, 2008·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·G BrohallB Fagerberg
Oct 29, 2005·The American Journal of Cardiology·Anna Kablak-ZiembickaAndrzej Sokolowski
Dec 5, 2014·International Journal of Behavioral Medicine·Andreas R SchwerdtfegerEva-Maria Rathner
Jan 6, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Peggy RobinetJonathan D Smith

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