Sex differences in hormonal responses to stress and smoking relapse: a prospective examination

Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco
Mustafa al'AbsiDorothy Hatsukami

Abstract

Dysregulation in the hypothalamic-pituitary-adrenal axis has been shown to be associated with smoking relapse. No study has directly examined the role of sex differences in this relationship. Nicotine dependent men (n = 52) and women (n = 46) interested in cessation completed 2 laboratory stress sessions during ad libitum smoking and after 48 hr of abstinence. The laboratory session included baseline, stress, and recovery periods. Blood and saliva samples were collected at the end of each period for the measurement of cortisol and adrenocorticotropic hormone. Self-report measures of craving and withdrawal symptoms were also collected. Participants attended 4 weekly follow-up sessions for counseling where they provided biological samples and self-report measures including smoking status. Relapse was defined by smoking cigarettes for 7 consecutive days post-cessation. Results showed that 60 participants relapsed during the 4-week period. Cox regression models from the abstinence session showed that cortisol levels regardless of source were predictive of relapse but the direction of prediction was sex dependent (Sex × Hormone, all ps < .05). Follow-up analyses further revealed that lower cortisol levels predicted relapse in men wh...Continue Reading

References

Sep 1, 1978·Journal of Health and Social Behavior·C Dicken
Dec 1, 1992·The Journal of Steroid Biochemistry and Molecular Biology·R A DressendörferC J Strasburger
Jan 1, 1992·Life Sciences·C KirschbaumC J Strasburger
Nov 1, 1991·British Journal of Addiction·S T Tiffany, D J Drobes
May 1, 1991·British Journal of Addiction·C S PomerleauA W Garcia
Sep 1, 1991·British Journal of Addiction·T F HeathertonK O Fagerström
Jan 1, 1990·European Journal of Clinical Pharmacology·M CurvallC R Enzell
Mar 1, 1986·Archives of General Psychiatry·J R Hughes, D Hatsukami
Jan 1, 1983·Psychopharmacology·O F PomerleauJ Jaffe
Dec 1, 1983·Journal of Health and Social Behavior·S CohenR Mermelstein
Dec 1, 1994·Psychopharmacology·K A PerkinsR L Stiller
Nov 1, 1993·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·G E SwanH S Javitz
Jul 1, 1997·Addictive Behaviors·K D WardA J Garvey
Oct 6, 1997·Science·G F Koob, M Le Moal
Apr 29, 1998·Trends in Pharmacological Sciences·P V Piazza, M Le Moal
Aug 26, 1998·Drug and Alcohol Dependence·M J Kreek, G F Koob
Aug 18, 1999·Journal of Consulting and Clinical Psychology·D W WetterT B Baker
Oct 9, 1999·Pharmacology, Biochemistry, and Behavior·K A Perkins
Nov 10, 2000·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·S S AllenD Nelson
Dec 26, 2001·Psychoneuroendocrinology·Maria Dorota Majewska
Dec 26, 2001·Psychoneuroendocrinology·Therese A Kosten, Emilio Ambrosio
Feb 28, 2002·Journal of Abnormal Psychology·Richard A BrownDavid R Strong
Aug 15, 2002·Pharmacology, Biochemistry, and Behavior·Sandra E FileElaine E Irvine
Aug 31, 2002·Psychopharmacology·Kenneth A PerkinsAnthony R Caggiula
Dec 14, 2002·Pharmacology, Biochemistry, and Behavior·Mustafa al'AbsiByron Crouse
Sep 25, 2003·Alcoholism, Clinical and Experimental Research·Bryon AdinoffMark J Williams
Nov 6, 2003·Experimental and Clinical Psychopharmacology·Thomas M PiaseckiTimothy B Baker
Jan 31, 2006·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Mustafa al'Absi
Jan 12, 2008·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Monica S Webb, Michael P Carey
Mar 1, 1993·Trends in Endocrinology and Metabolism : TEM·M F Dallman
Apr 23, 2008·The American Journal of Drug and Alcohol Abuse·Su-xia LiLin Lu
Dec 20, 2008·Psychoneuroendocrinology·Dirk H HellhammerBrigitte M Kudielka
May 5, 2009·Addictive Behaviors·Alicia M AllenMustafa Al'absi
Jun 18, 2010·The New England Journal of Medicine·Neal L Benowitz
Feb 23, 2012·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Motohiro Nakajima, Mustafa al'Absi
Jan 1, 2013·Biological Psychology·Mustafa al'AbsiJohn Grabowski
Apr 22, 2014·Addictive Behaviors·Rachel Isaksson VogelDorothy K Hatsukami

❮ Previous
Next ❯

Citations

Jan 26, 2016·Journal of Substance Abuse Treatment·Ivan BerlinStephen J Heishman
Jan 17, 2016·Pharmacological Reviews·Jill B Becker, George F Koob
Jan 2, 2016·Pharmacological Reviews·Styliani GoulopoulouR Clinton Webb
Apr 22, 2016·Addictive Behaviors·Andrine LemieuxMustafa al'Absi
Apr 19, 2016·Psychopharmacology·Rebecca L AshareJames Loughead
Nov 3, 2016·The American Journal of Drug and Alcohol Abuse·Matthew C MorrisUma Rao
Aug 4, 2016·Substance Use & Misuse·Nicole WiggertMustafa al'Absi
Aug 25, 2016·Substance Use & Misuse·Stephan BongardMustafa al'Absi
Apr 13, 2018·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Motohiro NakajimaMustafa al'Absi
Oct 27, 2017·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·C D C NevesV A Mendonça
Aug 24, 2017·Psychosomatic Medicine·Mustafa alʼAbsi
May 24, 2019·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Cheyenne AllenbyCaryn Lerman
Nov 12, 2019·European Journal of Public Health·Valérie OliéChristophe Bonaldi
Sep 7, 2017·Psychopharmacology·Mustafa al'AbsiSharon Allen
Jun 14, 2020·Substance Use & Misuse·Oscar V TorresIan Villalta
Jul 1, 2020·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Joseph W DitreJessica M Powers
Nov 8, 2019·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Ilze SlabbertAndrine M Lemieux
Nov 16, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Motohiro NakajimaMustafa al'Absi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology
Mustafa al'AbsiStephan Bongard
Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors
Motohiro Nakajima, Mustafa al'Absi
© 2021 Meta ULC. All rights reserved